2416 |
Entry |
2416 |
Residue(mutation) |
G243S |
Residue |
- |
Functionally important |
- |
Function of the protein |
transport; movement of ions across the cell membrane |
Location |
- |
Protein Name(abbreviation) |
Na-K-Cl cotransporter NKCC2B |
Source(scientific name) |
Oryctolagus cuniculus |
Source(english name) |
rabbit |
Authors |
Gim?nez I, Forbush B |
Journal Reference |
J Biol Chem. 2007 Mar 2;282(9):6540-7 |
PMID |
17186942 |
Experiments |
flux experiments |
Experimental data |
11.1 |
Parameter |
Km (mM) |
Methods/conditions |
kinetic analysis |
PDB ID |
- |
ASA |
- |
Sec. Str |
- |
Uniprot ID |
S12A1_RABIT (P55015) |
Type |
Helix |
Remarks |
- |
Keywords |
ion affinities; mutagenic approach; F variant; chloride inding; translocation domains |