312 |
Entry |
312 |
Residue(mutation) |
F594W |
Residue |
- |
Functionally important |
YES |
Function of the protein |
Substrate binding;transport |
Location |
TM 11; |
Protein Name(abbreviation) |
Multidrug resistance protein 1; MRP1 |
Source(scientific name) |
Homo sapiens |
Source(english name) |
Human |
Authors |
Campbell JD, Koike K, Moreau C, Sansom MS, Deeley RG, Cole SP. |
Journal Reference |
J Biol Chem. 2004 Jan 2;279(1):463-8 |
PMID |
14561746 |
Experiments |
mutagenesis |
Experimental data |
- |
Parameter |
uptake activity |
Methods/conditions |
- |
PDB ID |
2cbz |
ASA |
- |
Sec. Str |
- |
Uniprot ID |
MRP1_HUMAN (P33527) |
Type |
Helix |
Remarks |
- |
Keywords |
aromatic residue; uptake activity; transmembrane domain |