313
Entry 313
Residue(mutation) F594Y
Residue -
Functionally important YES
Function of the protein Substrate binding;transport
Location TM 11;
Protein Name(abbreviation) Multidrug resistance protein 1; MRP1
Source(scientific name) Homo sapiens
Source(english name) Human
Authors Campbell JD, Koike K, Moreau C, Sansom MS, Deeley RG, Cole SP.
Journal Reference J Biol Chem. 2004 Jan 2;279(1):463-8
PMID 14561746
Experiments mutagenesis
Experimental data -
Parameter uptake activity
Methods/conditions -
PDB ID 2cbz
ASA -
Sec. Str -
Uniprot ID MRP1_HUMAN (P33527)
Type Helix
Remarks -
Keywords aromatic residue; uptake activity; transmembrane domain