631 |
Entry |
631 |
Residue(mutation) |
I33S |
Residue |
- |
Functionally important |
yes |
Function of the protein |
binding site; nucleoside transport |
Location |
extracellular domain |
Protein Name(abbreviation) |
Human equilibrative nucleoside transporter 2; hENT2; |
Source(scientific name) |
Homo sapiens |
Source(english name) |
Human |
Authors |
Visser F, Zhang J, Raborn RT, Baldwin SA, Young JD, Cass CE. |
Journal Reference |
Mol Pharmacol. 2005 Apr;67(4):1291-8. |
PMID |
15644498 |
Experiments |
site-directed mutagenesis |
Experimental data |
67.1 |
Parameter |
Km (microM) |
Methods/conditions |
Kinetics (permeant: uridine) |
PDB ID |
- |
ASA |
- |
Sec. Str |
- |
Uniprot ID |
S29A2_HUMAN (Q14542) |
Type |
Helix |
Remarks |
- |
Keywords |
binding site; nucleoside permeants; transporter |