637
Entry 637
Residue(mutation) I33M
Residue -
Functionally important yes
Function of the protein binding site; nucleoside transport
Location extracellular domain
Protein Name(abbreviation) Human equilibrative nucleoside transporter 2; hENT2;
Source(scientific name) Homo sapiens
Source(english name) Human
Authors Visser F, Zhang J, Raborn RT, Baldwin SA, Young JD, Cass CE.
Journal Reference Mol Pharmacol. 2005 Apr;67(4):1291-8.
PMID 15644498
Experiments site-directed mutagenesis
Experimental data 2300
Parameter Vmax (pmol/mg/min)
Methods/conditions Kinetics (permeant: guanosine)
PDB ID -
ASA -
Sec. Str -
Uniprot ID S29A2_HUMAN (Q14542)
Type Helix
Remarks -
Keywords binding site; nucleoside permeants; transporter