| 735 | |
| Entry | 735 |
| Residue(mutation) | A443I;L447Y;Q448E |
| Residue | - |
| Functionally important | yes |
| Function of the protein | Corticosterone binding site |
| Location | TM10 |
| Protein Name(abbreviation) | Organic cation transporter; rOCT1 |
| Source(scientific name) | Rattus norvegicus |
| Source(english name) | Rat |
| Authors | Gorboulev V, Shatskaya N, Volk C, Koepsell H. |
| Journal Reference | Mol Pharmacol. 2005 May;67(5):1612-9 |
| PMID | 15662045 |
| Experiments | Tracer uptake measurements |
| Experimental data | 8.6 |
| Parameter | IC50 (microM) |
| Methods/conditions | Inhibition of MPP uptake |
| PDB ID | - |
| ASA | - |
| Sec. Str | - |
| Uniprot ID | O35882_RAT |
| Type | Helix |
| Remarks | - |
| Keywords | affinity; IC50; inhibition; substrate binding |