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NBDC - LSDB Archive
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AcEST | BlastX Result : Swiss-Prot | BlastX Result : TrEMBL | AcESTcontig | About Libraries
DK954452
Clone id TST39A01NGRL0020_H16
Library
Length 578
Definition Adiantum capillus-veneris mRNA. clone: TST39A01NGRL0020_H16. 5' end sequence.
Accession
Tissue type prothallia with plantlets
Developmental stage gametophytes with sporophytes
Contig ID
Sequence 
AGCAGTGTGGCAAATGGAGGATACTGTTCAGAAGCACGGTCAGGATGCGACAATTTGTTG
TCATGCCGGGGCATTGGCCACCCACTGCAGCAATAGAGGCGGTGGCTATTCCGGCAAGAA
GGCCATTTGGCAAGCCTCTGTCTATGATTTTGAAAGCCTGGAAGATTTTGAGGACGCTTC
CTTTGTCTACAGAAGATATGGATGTCCTAATGCAGAAGAGCTTGGTGCTGCGGTTGCTTC
TTTGGAAGGAGCAGAAGCAGGTCTGGCAACATCCACAGGCATGGGAGCAATCATTGCTGC
AGTCATGTCAATTTGTAAACAAGGAGATCTTATTATAGTTAATCCAGATGTCTATGGGGT
GACATATGAATTTTTCAAGACCGACATGGAGCGTTTTGGCATTGAAGTATTGTTTGAAAG
CATCTTCGAAGCACACATACTAGAGAACATTCTACAGAAAAATTTGGGAGAGCCGTCAAT
GGGTATGATCAAGCGAAGTGTGGTAGTGTTTTTAGAGTCGATCACGAATCCTTTTGGTTA
AGGTTGCAGACATATCTGCAATAGCCAAACTTTGCAAA
■■Homology search results ■■ -
sp_hit_id P55218
Definition sp|P55218|METZ_PSEAE O-succinylhomoserine sulfhydrylase OS=Pseudomonas aeruginosa
Align length 144
Score (bit) 73.2
E-value 9.0e-13
Report 
BLASTX 2.2.19 [Nov-02-2008]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= DK954452|Adiantum capillus-veneris mRNA, clone:
TST39A01NGRL0020_H16, 5'
         (578 letters)

Database: uniprot_sprot.fasta 
           412,525 sequences; 148,809,765 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

sp|P55218|METZ_PSEAE O-succinylhomoserine sulfhydrylase OS=Pseud...    73   9e-13
sp|O31632|METC_BACSU Cystathionine beta-lyase metC OS=Bacillus s...    67   8e-11
sp|P06106|MET17_YEAST Protein MET17 OS=Saccharomyces cerevisiae ...    66   1e-10
sp|P13254|MEGL_PSEPU Methionine gamma-lyase OS=Pseudomonas putid...    66   1e-10
sp|O31631|METB_BACSU Cystathionine gamma-synthase OS=Bacillus su...    63   9e-10
sp|O05394|MCCB_BACSU Cystathionine gamma-lyase OS=Bacillus subti...    62   2e-09
sp|O13326|CYSD_SCHPO O-acetylhomoserine (thiol)-lyase OS=Schizos...    60   8e-09
sp|Q92441|MET17_KLULA Protein MET17 OS=Kluyveromyces lactis GN=M...    59   1e-08
sp|Q8VCN5|CGL_MOUSE Cystathionine gamma-lyase OS=Mus musculus GN...    58   3e-08
sp|P32929|CGL_HUMAN Cystathionine gamma-lyase OS=Homo sapiens GN...    58   4e-08
sp|Q58DW2|CGL_BOVIN Cystathionine gamma-lyase OS=Bos taurus GN=C...    58   4e-08
sp|Q60HG7|CGL_MACFA Cystathionine gamma-lyase OS=Macaca fascicul...    57   5e-08
sp|P18757|CGL_RAT Cystathionine gamma-lyase OS=Rattus norvegicus...    55   3e-07
sp|Q19QT7|CGL_PIG Cystathionine gamma-lyase OS=Sus scrofa GN=CTH...    55   3e-07
sp|P00935|METB_ECOLI Cystathionine gamma-synthase OS=Escherichia...    53   1e-06
sp|P55217|METB_ARATH Cystathionine gamma-synthase, chloroplastic...    52   2e-06
sp|P24601|METB_HERAU Probable cystathionine gamma-synthase (Frag...    51   4e-06
sp|P31373|CYS3_YEAST Cystathionine gamma-lyase OS=Saccharomyces ...    51   4e-06
sp|P50125|CYSD_EMENI O-acetylhomoserine (thiol)-lyase OS=Emerice...    51   5e-06
sp|P56069|METB_HELPY Cystathionine gamma-synthase OS=Helicobacte...    49   2e-05
sp|Q52811|METC_RHIL3 Putative cystathionine beta-lyase OS=Rhizob...    47   5e-05
sp|Q9ZMW7|METB_HELPJ Cystathionine gamma-synthase OS=Helicobacte...    46   1e-04
sp|Q07703|METC_BORAV Cystathionine beta-lyase OS=Bordetella aviu...    44   6e-04
sp|P66875|METB_MYCTU Cystathionine gamma-synthase OS=Mycobacteri...    43   0.001
sp|P66876|METB_MYCBO Cystathionine gamma-synthase OS=Mycobacteri...    43   0.001
sp|P43623|METC_YEAST Putative cystathionine beta-lyase OS=Saccha...    43   0.001
sp|Q55DV9|CGL_DICDI Cystathionine gamma-lyase OS=Dictyostelium d...    42   0.002
sp|O94350|CBL_SCHPO Cystathionine beta-lyase OS=Schizosaccharomy...    42   0.002
sp|P44502|METB_HAEIN Cystathionine gamma-synthase OS=Haemophilus...    42   0.002
sp|P46807|METB_MYCLE Cystathionine gamma-synthase OS=Mycobacteri...    41   0.004

>sp|P55218|METZ_PSEAE O-succinylhomoserine sulfhydrylase
           OS=Pseudomonas aeruginosa GN=metZ PE=3 SV=1
          Length = 403

 Score = 73.2 bits (178), Expect = 9e-13
 Identities = 47/144 (32%), Positives = 72/144 (50%), Gaps = 6/144 (4%)
 Frame = +2

Query: 119 KAIWQASVYDFESLEDF------EDASFVYRRYGCPNAEELGAAVASLEGAEAGLATSTG 280
           +A++  S Y F +  D       E    VY RY  P        +A+LEGAE  +AT++G
Sbjct: 38  EALFTTSSYVFRTAADAAARFAGEVPGNVYSRYTNPTVRTFEERIAALEGAEQAVATASG 97

Query: 281 MGAIIAAVMSICKQGDLIIVNPDVYGVTYEFFKTDMERFGIEVLFESIFEAHILENILQK 460
           M AI+A VMS+C  GD ++V+  V+G T   F    +RFGI+V +  + +    E   + 
Sbjct: 98  MSAILALVMSLCSSGDHVLVSRSVFGSTISLFDKYFKRFGIQVDYPPLSDLAAWEAACKP 157

Query: 461 NLGEPSMGMIKRSVVVFLESITNP 532
           N           + + F+ES +NP
Sbjct: 158 N-----------TKLFFVESPSNP 170


>sp|O31632|METC_BACSU Cystathionine beta-lyase metC OS=Bacillus
           subtilis GN=metC PE=1 SV=1
          Length = 390

 Score = 66.6 bits (161), Expect = 8e-11
 Identities = 45/145 (31%), Positives = 71/145 (48%)
 Frame = +2

Query: 98  GGGYSGKKAIWQASVYDFESLEDFEDASFVYRRYGCPNAEELGAAVASLEGAEAGLATST 277
           GG  +    I  AS +   S E+F   ++ Y R G P    L   +A+LEG   G A S+
Sbjct: 21  GGTGAVSVPIQHASTFHQSSFEEF--GAYDYSRSGTPTRTALEETIAALEGGTRGFAFSS 78

Query: 278 GMGAIIAAVMSICKQGDLIIVNPDVYGVTYEFFKTDMERFGIEVLFESIFEAHILENILQ 457
           GM AI  A + +  QGD ++V  DVYG T+      + RFGIE  F  + + + +   ++
Sbjct: 79  GMAAISTAFL-LLSQGDHVLVTEDVYGGTFRMVTEVLTRFGIEHTFVDMTDRNEVARSIK 137

Query: 458 KNLGEPSMGMIKRSVVVFLESITNP 532
            N           + V+++E+ +NP
Sbjct: 138 PN-----------TKVIYMETPSNP 151


>sp|P06106|MET17_YEAST Protein MET17 OS=Saccharomyces cerevisiae
           GN=MET17 PE=1 SV=3
          Length = 444

 Score = 66.2 bits (160), Expect = 1e-10
 Identities = 52/169 (30%), Positives = 73/169 (43%), Gaps = 8/169 (4%)
 Frame = +2

Query: 50  TICCHAGALATHCSNRGGGYSGKKA--IWQASVYDFES------LEDFEDASFVYRRYGC 205
           T+  HAG       N G      +A  I+  + Y FE+      L   E   +VY R+  
Sbjct: 7   TVQLHAGQ-----ENPGDNAHRSRAVPIYATTSYVFENSKHGSQLFGLEVPGYVYSRFQN 61

Query: 206 PNAEELGAAVASLEGAEAGLATSTGMGAIIAAVMSICKQGDLIIVNPDVYGVTYEFFKTD 385
           P +  L   +A+LEG  A LA S+G  A   A+  +   GD I+    +YG TY  FK  
Sbjct: 62  PTSNVLEERIAALEGGAAALAVSSGQAAQTLAIQGLAHTGDNIVSTSYLYGGTYNQFKIS 121

Query: 386 MERFGIEVLFESIFEAHILENILQKNLGEPSMGMIKRSVVVFLESITNP 532
            +RFGIE  F         E +             +R+  V+LE+I NP
Sbjct: 122 FKRFGIEARFVEGDNPEEFEKVFD-----------ERTKAVYLETIGNP 159


>sp|P13254|MEGL_PSEPU Methionine gamma-lyase OS=Pseudomonas putida
           GN=mdeA PE=1 SV=2
          Length = 398

 Score = 66.2 bits (160), Expect = 1e-10
 Identities = 41/142 (28%), Positives = 69/142 (48%), Gaps = 6/142 (4%)
 Frame = +2

Query: 125 IWQASVYDFESLE------DFEDASFVYRRYGCPNAEELGAAVASLEGAEAGLATSTGMG 286
           ++Q + + F ++E        E A   Y R   P    L A +ASLEG EAGLA ++GMG
Sbjct: 32  VYQTATFTFPTVEYGAACFAGEQAGHFYSRISNPTLNLLEARMASLEGGEAGLALASGMG 91

Query: 287 AIIAAVMSICKQGDLIIVNPDVYGVTYEFFKTDMERFGIEVLFESIFEAHILENILQKNL 466
           AI + + ++ + GD +++   +YG T+ F    +  FG+++    + +   LE       
Sbjct: 92  AITSTLWTLLRPGDEVLLGNTLYGCTFAFLHHGIGEFGVKLRHVDMADLQALE------- 144

Query: 467 GEPSMGMIKRSVVVFLESITNP 532
                 M   + V++ ES  NP
Sbjct: 145 ----AAMTPATRVIYFESPANP 162


>sp|O31631|METB_BACSU Cystathionine gamma-synthase OS=Bacillus
           subtilis GN=metB PE=1 SV=1
          Length = 373

 Score = 63.2 bits (152), Expect = 9e-10
 Identities = 38/121 (31%), Positives = 63/121 (52%)
 Frame = +2

Query: 170 EDASFVYRRYGCPNAEELGAAVASLEGAEAGLATSTGMGAIIAAVMSICKQGDLIIVNPD 349
           E   F Y R   P  + +  A+A+LE    GLA S+GM AI   +M++ K GD +IV+ D
Sbjct: 40  ESTGFDYVRTKNPTRQLVEDAIANLENGARGLAFSSGMAAI-QTIMALFKSGDELIVSSD 98

Query: 350 VYGVTYEFFKTDMERFGIEVLFESIFEAHILENILQKNLGEPSMGMIKRSVVVFLESITN 529
           +YG TY  F+ + +++G+   ++   +   L + +  N           +  VF+E+ TN
Sbjct: 99  LYGGTYRLFENEWKKYGLTFHYDDFSDEDCLRSKITPN-----------TKAVFVETPTN 147

Query: 530 P 532
           P
Sbjct: 148 P 148


>sp|O05394|MCCB_BACSU Cystathionine gamma-lyase OS=Bacillus subtilis
           GN=mccB PE=1 SV=1
          Length = 379

 Score = 62.0 bits (149), Expect = 2e-09
 Identities = 43/136 (31%), Positives = 62/136 (45%)
 Frame = +2

Query: 125 IWQASVYDFESLEDFEDASFVYRRYGCPNAEELGAAVASLEGAEAGLATSTGMGAIIAAV 304
           I+Q S Y  +  +  +   + Y R   P    L A V  LE  EAG A S+GM AI  AV
Sbjct: 25  IYQVSTY--KQPKAGQHTGYEYSRTANPTRTALEALVTELESGEAGYAFSSGMAAI-TAV 81

Query: 305 MSICKQGDLIIVNPDVYGVTYEFFKTDMERFGIEVLFESIFEAHILENILQKNLGEPSMG 484
           M +   GD +++  DVYG TY      + R GIE  F        +E  ++ N       
Sbjct: 82  MMLFNSGDHVVLTDDVYGGTYRVMTKVLNRLGIESTFVDTSSREEVEKAIRPN------- 134

Query: 485 MIKRSVVVFLESITNP 532
               +  +++E+ TNP
Sbjct: 135 ----TKAIYIETPTNP 146


>sp|O13326|CYSD_SCHPO O-acetylhomoserine (thiol)-lyase
           OS=Schizosaccharomyces pombe GN=SPBC428.11 PE=2 SV=1
          Length = 429

 Score = 60.1 bits (144), Expect = 8e-09
 Identities = 36/121 (29%), Positives = 60/121 (49%)
 Frame = +2

Query: 170 EDASFVYRRYGCPNAEELGAAVASLEGAEAGLATSTGMGAIIAAVMSICKQGDLIIVNPD 349
           ++  ++Y R   P A+     +A+LE   A +ATS+G  A+  A+ ++ K GD I+    
Sbjct: 51  QEPGYIYSRMMNPTADVFEKRIAALEHGAAAIATSSGTSALFMALTTLAKAGDNIVSTSY 110

Query: 350 VYGVTYEFFKTDMERFGIEVLFESIFEAHILENILQKNLGEPSMGMIKRSVVVFLESITN 529
           +YG TY  FK  + R GI   F +  + + L   + +N           +  V++ESI N
Sbjct: 111 LYGGTYNLFKVTLPRLGITTKFVNGDDPNDLAAQIDEN-----------TKAVYVESIGN 159

Query: 530 P 532
           P
Sbjct: 160 P 160


>sp|Q92441|MET17_KLULA Protein MET17 OS=Kluyveromyces lactis
           GN=MET17 PE=3 SV=3
          Length = 444

 Score = 59.3 bits (142), Expect = 1e-08
 Identities = 39/121 (32%), Positives = 56/121 (46%)
 Frame = +2

Query: 170 EDASFVYRRYGCPNAEELGAAVASLEGAEAGLATSTGMGAIIAAVMSICKQGDLIIVNPD 349
           E   ++Y R   P  + L   +A+LEG  A LATS+G  A   AV  +   GD I+    
Sbjct: 49  ETPGYIYSRIMNPTLDVLEKRLAALEGGIAALATSSGQAAQTLAVTGLAHTGDNIVSTSF 108

Query: 350 VYGVTYEFFKTDMERFGIEVLFESIFEAHILENILQKNLGEPSMGMIKRSVVVFLESITN 529
           +YG TY  FK   +R GIE  F    +    E +             +++  ++LESI N
Sbjct: 109 LYGGTYNQFKVAFKRLGIEARFVDGDKPEDFEKLFD-----------EKTKALYLESIGN 157

Query: 530 P 532
           P
Sbjct: 158 P 158


>sp|Q8VCN5|CGL_MOUSE Cystathionine gamma-lyase OS=Mus musculus
           GN=Cth PE=1 SV=1
          Length = 398

 Score = 58.2 bits (139), Expect = 3e-08
 Identities = 39/126 (30%), Positives = 65/126 (51%), Gaps = 2/126 (1%)
 Frame = +2

Query: 161 EDF--EDASFVYRRYGCPNAEELGAAVASLEGAEAGLATSTGMGAIIAAVMSICKQGDLI 334
           +DF  + + F Y R G P    L  AVA+L+GA+  LA ++G+ A I  +  + K GD I
Sbjct: 48  QDFPGQSSGFEYSRSGNPTRNCLEKAVAALDGAKHSLAFASGLAATI-TITHLLKAGDEI 106

Query: 335 IVNPDVYGVTYEFFKTDMERFGIEVLFESIFEAHILENILQKNLGEPSMGMIKRSVVVFL 514
           I   +VYG T  +F+     FG+++ F    +  +LE             +  ++ +V++
Sbjct: 107 ICMDEVYGGTNRYFRRVASEFGLKISFVDCSKTKLLE-----------AAITPQTKLVWI 155

Query: 515 ESITNP 532
           E+ TNP
Sbjct: 156 ETPTNP 161


>sp|P32929|CGL_HUMAN Cystathionine gamma-lyase OS=Homo sapiens
           GN=CTH PE=1 SV=3
          Length = 405

 Score = 57.8 bits (138), Expect = 4e-08
 Identities = 41/134 (30%), Positives = 65/134 (48%), Gaps = 5/134 (3%)
 Frame = +2

Query: 170 EDASFVYRRYGCPNAEELGAAVASLEGAEAGLATSTGMGAIIAAVMSICKQGDLIIVNPD 349
           + + F Y R G P    L  AVA+L+GA+  LA ++G+ A +  +  + K GD II   D
Sbjct: 54  QHSGFEYSRSGNPTRNCLEKAVAALDGAKYCLAFASGLAATVT-ITHLLKAGDQIICMDD 112

Query: 350 VYGVTYEFFKTDMERFGIEVLFESIFEAHILENILQKNLGEPSMGMIKRSVVVFLESITN 529
           VYG T  +F+     FG+++ F    +  +LE             +   + +V++E+ TN
Sbjct: 113 VYGGTNRYFRQVASEFGLKISFVDCSKIKLLE-----------AAITPETKLVWIETPTN 161

Query: 530 PFG-----*GCRHI 556
           P        GC HI
Sbjct: 162 PTQKVIDIEGCAHI 175
tr_hit_id A8VUM3
Definition tr|A8VUM3|A8VUM3_9BACI Dihydrodipicolinate synthase OS=Bacillus selenitireducens MLS10
Align length 149
Score (bit) 105.0
E-value 1.0e-21
Report 
BLASTX 2.2.19 [Nov-02-2008]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= DK954452|Adiantum capillus-veneris mRNA, clone:
TST39A01NGRL0020_H16, 5'
         (578 letters)

Database: uniprot_trembl.fasta 
           7,341,751 sequences; 2,391,615,440 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

tr|A8VUM3|A8VUM3_9BACI Dihydrodipicolinate synthase OS=Bacillus ...   105   1e-21
tr|Q9KFD9|Q9KFD9_BACHD Cystathionine gamma-synthase OS=Bacillus ...    99   1e-19
tr|A6CNA1|A6CNA1_9BACI Cystathionine gamma-synthase OS=Bacillus ...    99   2e-19
tr|Q5WJQ0|Q5WJQ0_BACSK Cystathionine gamma-lyase OS=Bacillus cla...    98   4e-19
tr|A0M3E5|A0M3E5_GRAFK Methionine gamma-lyase OS=Gramella forset...    88   3e-16
tr|Q5QU17|Q5QU17_IDILO Methionine gamma-lyase OS=Idiomarina loih...    88   4e-16
tr|Q8RDT4|Q8RDT4_FUSNN Methionine gamma-lyase OS=Fusobacterium n...    84   7e-15
tr|B0K2T5|B0K2T5_THEPX Cystathionine gamma-synthase OS=Thermoana...    84   7e-15
tr|Q3IIZ1|Q3IIZ1_PSEHT Probable Methionine gamma-lyase OS=Pseudo...    83   1e-14
tr|B0K8U0|B0K8U0_THEP3 Cystathionine gamma-synthase OS=Thermoana...    83   1e-14
tr|Q8L0X4|Q8L0X4_FUSNU L-methionine-alpha-deamino-gamma-mercapto...    83   1e-14
tr|A5TY55|A5TY55_FUSNP Methionine gamma-lyase OS=Fusobacterium n...    83   1e-14
tr|A0Y3T5|A0Y3T5_9GAMM Probable Methionine gamma-lyase OS=Altero...    83   1e-14
tr|Q8R9N2|Q8R9N2_THETN Cystathionine beta-lyases/cystathionine g...    82   2e-14
tr|B7R768|B7R768_9THEO Cys/Met metabolism PLP-dependent enzyme s...    82   2e-14
tr|Q1IZN0|Q1IZN0_DEIGD Cystathionine gamma-synthase OS=Deinococc...    81   5e-14
tr|B1L1M5|B1L1M5_CLOBM Methionine gamma-lyase OS=Clostridium bot...    80   6e-14
tr|A3UAN3|A3UAN3_9FLAO Cys/Met metabolism lyase (PLP-dependent) ...    80   6e-14
tr|B1QR17|B1QR17_CLOBO L-cystine import ATP-binding protein TcyN...    80   8e-14
tr|B3Q9B1|B3Q9B1_RHOPT Methionine gamma-lyase OS=Rhodopseudomona...    79   1e-13
tr|A4CDA9|A4CDA9_9GAMM Probable Methionine gamma-lyase OS=Pseudo...    79   2e-13
tr|A5UJK1|A5UJK1_METS3 O-acetylhomoserine sulfhydrylase (PLP-dep...    79   2e-13
tr|B6W9L2|B6W9L2_9FIRM Putative uncharacterized protein OS=Anaer...    78   3e-13
tr|A4CKV8|A4CKV8_9FLAO Cystathionine beta-lyase OS=Robiginitalea...    78   3e-13
tr|Q0HHB9|Q0HHB9_SHESM Methionine gamma-lyase OS=Shewanella sp. ...    78   4e-13
tr|A0KYK1|A0KYK1_SHESA Methionine gamma-lyase OS=Shewanella sp. ...    78   4e-13
tr|B7RU67|B7RU67_9GAMM O-succinylhomoserine sulfhydrylase OS=mar...    78   4e-13
tr|A9EC23|A9EC23_9FLAO Methionine gamma-lyase OS=Kordia algicida...    78   4e-13
tr|Q9ZFY1|Q9ZFY1_PSEAC MetZ homolog (Fragment) OS=Pseudomonas al...    77   5e-13
tr|B0A7L1|B0A7L1_9CLOT Putative uncharacterized protein OS=Clost...    77   5e-13

>tr|A8VUM3|A8VUM3_9BACI Dihydrodipicolinate synthase OS=Bacillus
           selenitireducens MLS10 GN=BselDRAFT_1859 PE=3 SV=1
          Length = 377

 Score =  105 bits (263), Expect = 1e-21
 Identities = 57/149 (38%), Positives = 88/149 (59%), Gaps = 5/149 (3%)
 Frame = +2

Query: 101 GGYSGKKAIWQASVYDFESLEDFE-----DASFVYRRYGCPNAEELGAAVASLEGAEAGL 265
           G YS    I+Q S + F+ ++D E     D S++Y R G PN +ELG AVA+LEGAEAG+
Sbjct: 17  GEYSKTTPIYQTSAFAFKDIDDMEQYFNGDKSYLYTRMGNPNTDELGQAVAALEGAEAGV 76

Query: 266 ATSTGMGAIIAAVMSICKQGDLIIVNPDVYGVTYEFFKTDMERFGIEVLFESIFEAHILE 445
           A+S+G+ AI+A  +S+ K GD +IV  D+YG T++    +++  GI V F  +       
Sbjct: 77  ASSSGLSAILAGFLSVAKPGDHVIVAEDLYGGTFQLINDEIQGLGIRVTFMDM------- 129

Query: 446 NILQKNLGEPSMGMIKRSVVVFLESITNP 532
                N+ +    +   +V+++ ESITNP
Sbjct: 130 ----TNVKDVEAAITADTVMIYTESITNP 154


>tr|Q9KFD9|Q9KFD9_BACHD Cystathionine gamma-synthase OS=Bacillus
           halodurans GN=BH0542 PE=3 SV=1
          Length = 381

 Score = 99.4 bits (246), Expect = 1e-19
 Identities = 52/146 (35%), Positives = 87/146 (59%), Gaps = 5/146 (3%)
 Frame = +2

Query: 110 SGKKAIWQASVYDFESLEDFE-----DASFVYRRYGCPNAEELGAAVASLEGAEAGLATS 274
           S  K I+Q S + F+ L+D E     +  ++Y RYG PN+++LG  VASLE AE G+ATS
Sbjct: 23  SKSKPIYQTSAFVFQDLDDMESFYRGEKEYLYTRYGNPNSDDLGKGVASLEQAEDGVATS 82

Query: 275 TGMGAIIAAVMSICKQGDLIIVNPDVYGVTYEFFKTDMERFGIEVLFESIFEAHILENIL 454
            GM AI+ A++++ ++GD +I   D+YG TY+    ++ + GI+V F    E  +++  +
Sbjct: 83  AGMSAILVALLALLEKGDHLIAANDLYGGTYQLLAEELPKLGIDVSFVPFQEREVVKRAI 142

Query: 455 QKNLGEPSMGMIKRSVVVFLESITNP 532
           +           K + V++ E++TNP
Sbjct: 143 R-----------KETKVLYSETVTNP 157


>tr|A6CNA1|A6CNA1_9BACI Cystathionine gamma-synthase OS=Bacillus sp.
           SG-1 GN=BSG1_09031 PE=3 SV=1
          Length = 376

 Score = 98.6 bits (244), Expect = 2e-19
 Identities = 53/142 (37%), Positives = 83/142 (58%), Gaps = 5/142 (3%)
 Frame = +2

Query: 125 IWQASVYDFESLEDFE-----DASFVYRRYGCPNAEELGAAVASLEGAEAGLATSTGMGA 289
           I+Q S + F SLE+ E     ++ ++Y R G PN +ELG  VA LEGA AG+A ++G+GA
Sbjct: 24  IYQTSAFSFSSLEELEGFYEGNSPYLYTRSGNPNTDELGDMVAVLEGAPAGVAAASGLGA 83

Query: 290 IIAAVMSICKQGDLIIVNPDVYGVTYEFFKTDMERFGIEVLFESIFEAHILENILQKNLG 469
           I+A ++++ + GD II   D+YG TY     +++ FGI V F    +   +EN +     
Sbjct: 84  ILAGILAVAESGDHIIAAEDIYGGTYHLLNEELKFFGITVSFVDFSDPQEIENTI----- 138

Query: 470 EPSMGMIKRSVVVFLESITNPF 535
                   ++ +++ ESITNPF
Sbjct: 139 ------TPQTKLLYSESITNPF 154


>tr|Q5WJQ0|Q5WJQ0_BACSK Cystathionine gamma-lyase OS=Bacillus
           clausii (strain KSM-K16) GN=ABC0866 PE=3 SV=1
          Length = 378

 Score = 97.8 bits (242), Expect = 4e-19
 Identities = 59/151 (39%), Positives = 85/151 (56%), Gaps = 5/151 (3%)
 Frame = +2

Query: 95  RGGGYSGKKAIWQASVYDFESLEDFE-----DASFVYRRYGCPNAEELGAAVASLEGAEA 259
           +G   S  + I+Q S + F+ L D E     +  ++Y RYG PN ++LG  VA LE AE 
Sbjct: 17  KGENQSKARPIYQTSAFVFKDLADMEQYFKGEKDYLYTRYGNPNTDDLGKGVALLECAED 76

Query: 260 GLATSTGMGAIIAAVMSICKQGDLIIVNPDVYGVTYEFFKTDMERFGIEVLFESIFEAHI 439
           G+ATS+GM AI+ A+++ CK GD +I   DVYG TY   + ++  FGIEV F      H 
Sbjct: 77  GVATSSGMSAILCAILAFCKTGDHLIATMDVYGGTYALLEKELSLFGIEVSF-----VHP 131

Query: 440 LENILQKNLGEPSMGMIKRSVVVFLESITNP 532
            EN  + ++   + G       VF E+I+NP
Sbjct: 132 NEN-WEASIKSNTKG-------VFAETISNP 154


>tr|A0M3E5|A0M3E5_GRAFK Methionine gamma-lyase OS=Gramella forsetii
           (strain KT0803) GN=mdeA PE=3 SV=1
          Length = 404

 Score = 88.2 bits (217), Expect = 3e-16
 Identities = 45/128 (35%), Positives = 73/128 (57%)
 Frame = +2

Query: 149 FESLEDFEDASFVYRRYGCPNAEELGAAVASLEGAEAGLATSTGMGAIIAAVMSICKQGD 328
           F++ E   +  ++Y R+  P+   LG A+A++EG E    +++GMGAI + +M +C  GD
Sbjct: 40  FDTFEGNAEGCYLYSRHSSPSNLYLGEALAAMEGTETANVSASGMGAITSVLMQLCNAGD 99

Query: 329 LIIVNPDVYGVTYEFFKTDMERFGIEVLFESIFEAHILENILQKNLGEPSMGMIKRSVVV 508
            I+ +  VYG TY F K    +FGIE  F  I +  I++N +QKN           + V+
Sbjct: 100 HIVCSRTVYGGTYAFLKNFAPKFGIETTFVDITKPEIVKNAVQKN-----------TKVI 148

Query: 509 FLESITNP 532
           + ES++NP
Sbjct: 149 YCESVSNP 156


>tr|Q5QU17|Q5QU17_IDILO Methionine gamma-lyase OS=Idiomarina
           loihiensis GN=IL0726 PE=3 SV=1
          Length = 408

 Score = 87.8 bits (216), Expect = 4e-16
 Identities = 60/170 (35%), Positives = 85/170 (50%), Gaps = 6/170 (3%)
 Frame = +2

Query: 41  QDATICCHAGALATHCSNRGGGYSGKKAIWQASVYDFESLEDF------EDASFVYRRYG 202
           Q AT   HAGA   H    G   +    ++Q S + F S E        E+  ++Y R G
Sbjct: 13  QPATQVIHAGA--AHDDPHGALTA---PLYQTSTFRFSSAEQGTRRFAGEEEGYIYSRLG 67

Query: 203 CPNAEELGAAVASLEGAEAGLATSTGMGAIIAAVMSICKQGDLIIVNPDVYGVTYEFFKT 382
            P   EL   +ASLEG EA  A +TGMGAI AA M+  + GD I+V+  +YG ++  F  
Sbjct: 68  NPTTAELERRMASLEGYEAAAAAATGMGAIAAATMAFVRSGDHIVVSDAIYGCSFALFSE 127

Query: 383 DMERFGIEVLFESIFEAHILENILQKNLGEPSMGMIKRSVVVFLESITNP 532
             ERFG+E  F  +    +L+  L++N           + +VFLE+  NP
Sbjct: 128 LFERFGVEADFIDLNNEGLLKETLREN-----------TRLVFLETPANP 166


>tr|Q8RDT4|Q8RDT4_FUSNN Methionine gamma-lyase OS=Fusobacterium
           nucleatum subsp. nucleatum GN=FN1419 PE=3 SV=1
          Length = 395

 Score = 83.6 bits (205), Expect = 7e-15
 Identities = 49/142 (34%), Positives = 74/142 (52%), Gaps = 6/142 (4%)
 Frame = +2

Query: 125 IWQASVYDFESLED------FEDASFVYRRYGCPNAEELGAAVASLEGAEAGLATSTGMG 286
           I+Q S + F+S E        E+A ++Y R G P    L   +A+LE  EAG+A S+GMG
Sbjct: 29  IYQTSTFIFDSAEQGGRRFALEEAGYIYTRLGNPTTTVLENKIAALEEGEAGIAMSSGMG 88

Query: 287 AIIAAVMSICKQGDLIIVNPDVYGVTYEFFKTDMERFGIEVLFESIFEAHILENILQKNL 466
           AI + + ++ K GD ++ +  +YG T+      + RFG+EV F           +   NL
Sbjct: 89  AISSTLWTVLKAGDHVVTDKTLYGCTFALMNHGLTRFGVEVTF-----------VDTSNL 137

Query: 467 GEPSMGMIKRSVVVFLESITNP 532
            E    M K + VV+LE+  NP
Sbjct: 138 EEVKNAMKKNTRVVYLETPANP 159


>tr|B0K2T5|B0K2T5_THEPX Cystathionine gamma-synthase
           OS=Thermoanaerobacter sp. (strain X514) GN=Teth514_1860
           PE=3 SV=1
          Length = 393

 Score = 83.6 bits (205), Expect = 7e-15
 Identities = 48/142 (33%), Positives = 76/142 (53%), Gaps = 6/142 (4%)
 Frame = +2

Query: 125 IWQASVYDFESLEDFED------ASFVYRRYGCPNAEELGAAVASLEGAEAGLATSTGMG 286
           I+Q SV+ F++LE+  D      + ++Y R G PN   +   +ASLEGAEAG A S+GM 
Sbjct: 29  IYQTSVFTFDTLEEVYDYLGGNPSRYMYTRLGNPNQTAVEELIASLEGAEAGQACSSGMA 88

Query: 287 AIIAAVMSICKQGDLIIVNPDVYGVTYEFFKTDMERFGIEVLFESIFEAHILENILQKNL 466
           AI +A+++    GD II   D+YG T   F  + +R  I+V      +   +E  ++ N 
Sbjct: 89  AIFSALLAEVNSGDHIIAAKDIYGGTNSLFNAEFKRLNIDVTLVDFSDLEAVEKAIKPN- 147

Query: 467 GEPSMGMIKRSVVVFLESITNP 532
                     + V+++E +TNP
Sbjct: 148 ----------TKVIYMEIMTNP 159


>tr|Q3IIZ1|Q3IIZ1_PSEHT Probable Methionine gamma-lyase
           OS=Pseudoalteromonas haloplanktis (strain TAC 125)
           GN=mdeA PE=3 SV=1
          Length = 393

 Score = 82.8 bits (203), Expect = 1e-14
 Identities = 49/142 (34%), Positives = 74/142 (52%), Gaps = 6/142 (4%)
 Frame = +2

Query: 125 IWQASVYDFESLEDF------EDASFVYRRYGCPNAEELGAAVASLEGAEAGLATSTGMG 286
           ++Q S + FE+          ++  ++Y R G P   EL   VA LEG EA  AT+TGMG
Sbjct: 28  LYQTSTFHFENAAQGAARFAGDEPGYIYTRLGNPTTTELEQKVAQLEGCEAAAATATGMG 87

Query: 287 AIIAAVMSICKQGDLIIVNPDVYGVTYEFFKTDMERFGIEVLFESIFEAHILENILQKNL 466
           A+ A+V+S   QGD +I +  +YG T+ FF   + R+GIEV F  +     L   ++ N 
Sbjct: 88  AVSASVLSFLSQGDHLIASSALYGCTFAFFSHMLPRWGIEVTFVDMTNEDELRAAIKPN- 146

Query: 467 GEPSMGMIKRSVVVFLESITNP 532
                     S ++F+E+  NP
Sbjct: 147 ----------SKMIFVETPINP 158


>tr|B0K8U0|B0K8U0_THEP3 Cystathionine gamma-synthase
           OS=Thermoanaerobacter pseudethanolicus (strain ATCC
           33223 / 39E) GN=Teth39_0897 PE=3 SV=1
          Length = 393

 Score = 82.8 bits (203), Expect = 1e-14
 Identities = 48/142 (33%), Positives = 76/142 (53%), Gaps = 6/142 (4%)
 Frame = +2

Query: 125 IWQASVYDFESLEDFED------ASFVYRRYGCPNAEELGAAVASLEGAEAGLATSTGMG 286
           I+Q SV+ F++LE+  D      + ++Y R G PN   +   +ASLEGAEAG A S+GM 
Sbjct: 29  IYQTSVFTFDTLEEVYDYLGGNPSRYMYTRLGNPNQTAVEELIASLEGAEAGQACSSGMA 88

Query: 287 AIIAAVMSICKQGDLIIVNPDVYGVTYEFFKTDMERFGIEVLFESIFEAHILENILQKNL 466
           AI +A+++    GD II   D+YG T   F  + +R  I+V      +   +E  ++ N 
Sbjct: 89  AISSALLAEVNSGDHIIAAKDIYGGTNSLFNAEFKRLNIDVTLVDFSDLEAVEKAIKPN- 147

Query: 467 GEPSMGMIKRSVVVFLESITNP 532
                     + V+++E +TNP
Sbjct: 148 ----------TKVIYMEIMTNP 159