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NBDC - LSDB Archive
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AcEST | BlastX Result : Swiss-Prot | BlastX Result : TrEMBL | AcESTcontig | About Libraries
DK960408
Clone id TST39A01NGRL0007_F10
Library
Length 438
Definition Adiantum capillus-veneris mRNA. clone: TST39A01NGRL0007_F10. 5' end sequence.
Accession
Tissue type prothallia with plantlets
Developmental stage gametophytes with sporophytes
Contig ID
Sequence 
CGAATGTGAAGAAACCATCTTACAAGATGTCAACATGGACGAGGAAATGAGGAGGAAGCA
GCAGCAACAGAGCCATGAAGCTTATGAGGAAGACGAGGAAGGTGGTTCTGGGCCAAGAGT
GCAGTGTGCTCAACAGTAAGAGTACGACTTATGAAAGTCCAAGTGGGATTGAAATTCCAT
TTAAGTAGTTCTCCCCCCTCAACTGGTGTGAGGAACAGGTTTCTTTTAATAGCTTGTCTT
GCAGCGAAGACTGCCTTGGATACATCCCATGGACATAACTAATGCTCATCAGTCATCTTT
AGACTAGATGGTGTGCCGTTAGGTTTTGAAGATGTGCTGGTATAGGATTTTTGGGCGTGT
ATTGTAATTTGGGTACCATACTGTTTTATCATTTAAAAAGAACTTCTGATTGTTAAAAAA
AAAAAAAAAAAAAAAAAA
■■Homology search results ■■ -
sp_hit_id Q03363
Definition sp|Q03363|DNJH1_ALLPO DnaJ protein homolog 1 (Fragment) OS=Allium porrum
Align length 46
Score (bit) 69.3
E-value 6.0e-12
Report 
BLASTX 2.2.19 [Nov-02-2008]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= DK960408|Adiantum capillus-veneris mRNA, clone:
TST39A01NGRL0007_F10, 5'
         (414 letters)

Database: uniprot_sprot.fasta 
           412,525 sequences; 148,809,765 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

sp|Q03363|DNJH1_ALLPO DnaJ protein homolog 1 (Fragment) OS=Alliu...    69   6e-12
sp|P42824|DNJH2_ALLPO DnaJ protein homolog 2 OS=Allium porrum GN...    69   7e-12
sp|P43644|DNJH_ATRNU DnaJ protein homolog ANJ1 OS=Atriplex nummu...    65   1e-10
sp|Q04960|DNJH_CUCSA DnaJ protein homolog OS=Cucumis sativus GN=...    59   1e-08
sp|Q94AW8|DNAJ3_ARATH Chaperone protein dnaJ 3 OS=Arabidopsis th...    56   6e-08
sp|P42825|DNAJ2_ARATH Chaperone protein dnaJ 2 OS=Arabidopsis th...    55   8e-08
sp|Q873X0|PACC_GIBMO pH-response transcription factor pacC/RIM10...    34   0.26 
sp|Q8BQ48|K1731_MOUSE Leucine-rich repeat-containing protein KIA...    32   0.76 
sp|Q7SGG0|SRB8_NEUCR Mediator of RNA polymerase II transcription...    30   3.8  
sp|Q8A0Y9|REX_BACTN Redox-sensing transcriptional repressor rex ...    30   3.8  
sp|Q823B7|KTHY_CHLCV Thymidylate kinase OS=Chlamydophila caviae ...    30   3.8  
sp|P02858|GLYG4_SOYBN Glycinin G4 OS=Glycine max GN=GY4 PE=1 SV=1      30   4.9  
sp|Q9HRY3|DNAJ_HALSA Chaperone protein dnaJ OS=Halobacterium sal...    30   4.9  
sp|Q9P6R2|YOH8_SCHPO Uncharacterized protein C13E7.08c OS=Schizo...    29   6.5  
sp|Q9Y6F6|MRVI1_HUMAN Protein MRVI1 OS=Homo sapiens GN=MRVI1 PE=...    29   6.5  
sp|O74752|MAS5_SCHPO Mitochondrial protein import protein mas5 O...    29   6.5  
sp|Q8VDQ9|KRI1_MOUSE Protein KRI1 homolog OS=Mus musculus GN=Kri...    29   6.5  
sp|Q8N9T8|KRI1_HUMAN Protein KRI1 homolog OS=Homo sapiens GN=KRI...    29   6.5  
sp|A7F8V8|DBP7_SCLS1 ATP-dependent RNA helicase dbp7 OS=Scleroti...    29   6.5  
sp|Q7ZTY4|RBBP7_DANRE Histone-binding protein RBBP7 OS=Danio rer...    29   8.4  
sp|Q5L5Y4|KTHY_CHLAB Thymidylate kinase OS=Chlamydophila abortus...    29   8.4  

>sp|Q03363|DNJH1_ALLPO DnaJ protein homolog 1 (Fragment) OS=Allium
           porrum GN=DNAJ1 PE=2 SV=1
          Length = 397

 Score = 69.3 bits (168), Expect = 6e-12
 Identities = 32/46 (69%), Positives = 38/46 (82%), Gaps = 1/46 (2%)
 Frame = +2

Query: 2   ECEETILQDVNMDEEMRRKQQQQSHEAYEEDEEG-GSGPRVQCAQQ 136
           ECEET + DVN++EEMRRKQ Q + EAY+ED+EG G G RVQCAQQ
Sbjct: 352 ECEETTMHDVNIEEEMRRKQHQHAQEAYDEDDEGHGGGQRVQCAQQ 397


>sp|P42824|DNJH2_ALLPO DnaJ protein homolog 2 OS=Allium porrum
           GN=LDJ2 PE=2 SV=1
          Length = 418

 Score = 68.9 bits (167), Expect = 7e-12
 Identities = 32/46 (69%), Positives = 38/46 (82%), Gaps = 1/46 (2%)
 Frame = +2

Query: 2   ECEETILQDVNMDEEMRRKQQQQSHEAYEEDEEG-GSGPRVQCAQQ 136
           ECEET + DVN++EEMRRKQ QQ+ EAY+ED+EG G   RVQCAQQ
Sbjct: 373 ECEETTMHDVNIEEEMRRKQHQQAQEAYDEDDEGHGGAQRVQCAQQ 418


>sp|P43644|DNJH_ATRNU DnaJ protein homolog ANJ1 OS=Atriplex
           nummularia PE=2 SV=1
          Length = 417

 Score = 65.1 bits (157), Expect = 1e-10
 Identities = 29/45 (64%), Positives = 35/45 (77%)
 Frame = +2

Query: 2   ECEETILQDVNMDEEMRRKQQQQSHEAYEEDEEGGSGPRVQCAQQ 136
           ECEET L +VN++EEM+RKQ Q   EAY+ED+E   G RVQCAQQ
Sbjct: 373 ECEETTLHNVNIEEEMKRKQTQAQQEAYDEDDEPAGGQRVQCAQQ 417


>sp|Q04960|DNJH_CUCSA DnaJ protein homolog OS=Cucumis sativus
           GN=DNAJ1 PE=2 SV=1
          Length = 413

 Score = 58.5 bits (140), Expect = 1e-08
 Identities = 31/46 (67%), Positives = 35/46 (76%), Gaps = 1/46 (2%)
 Frame = +2

Query: 2   ECEETILQDVNMDEEMRRKQQQQSHEAYEEDEE-GGSGPRVQCAQQ 136
           ECEET L DVN++EEMRRKQ Q   EAY+EDE+  G   RVQCAQQ
Sbjct: 371 ECEETTLHDVNIEEEMRRKQAQ---EAYDEDEDMHGGAQRVQCAQQ 413


>sp|Q94AW8|DNAJ3_ARATH Chaperone protein dnaJ 3 OS=Arabidopsis
           thaliana GN=ATJ3 PE=1 SV=2
          Length = 420

 Score = 55.8 bits (133), Expect = 6e-08
 Identities = 29/49 (59%), Positives = 35/49 (71%), Gaps = 4/49 (8%)
 Frame = +2

Query: 2   ECEETILQDVNMDEEMRRKQQQQSHEAYEEDEEG----GSGPRVQCAQQ 136
           ECEET L DVN+++EMRRK Q Q  EAY++D+E     G   RVQCAQQ
Sbjct: 373 ECEETTLHDVNIEDEMRRKAQAQ-REAYDDDDEDDDHPGGAQRVQCAQQ 420


>sp|P42825|DNAJ2_ARATH Chaperone protein dnaJ 2 OS=Arabidopsis
           thaliana GN=ATJ2 PE=1 SV=2
          Length = 419

 Score = 55.5 bits (132), Expect = 8e-08
 Identities = 28/47 (59%), Positives = 35/47 (74%), Gaps = 2/47 (4%)
 Frame = +2

Query: 2   ECEETILQDVNMDEEMRRKQQQQSHEAYEEDEEG--GSGPRVQCAQQ 136
           +CEET L DVN+++EM+RK Q Q  EAY++DEE   G   RVQCAQQ
Sbjct: 374 DCEETTLHDVNIEDEMKRKAQAQ-REAYDDDEEDHPGGAQRVQCAQQ 419


>sp|Q873X0|PACC_GIBMO pH-response transcription factor pacC/RIM101
           OS=Gibberella moniliformis GN=PAC1 PE=3 SV=1
          Length = 613

 Score = 33.9 bits (76), Expect = 0.26
 Identities = 29/106 (27%), Positives = 46/106 (43%), Gaps = 2/106 (1%)
 Frame = -2

Query: 347 SYTSTSSKPNGTPSSLKMTDEH*LCPWDVSKAVFAARQAIKRNLFLTPVEGGELLKWNFN 168
           S TS++S+ +  PS+   +D++ +C W+     F A +A+  ++    V        N  
Sbjct: 44  SATSSTSQSSTAPST--SSDDNLICRWNACNQKFPAPEALYEHICERHVGRKSTNNLNLT 101

Query: 167 PTWTFISRTLTV--EHTALLAQNHLPRLPHKLHGSVAAASSSFPRP 36
             W    RT TV  +H     + H+P  PHK          SF RP
Sbjct: 102 CQWN-SCRTTTVKRDHITSHIRVHVPLKPHKCE----FCGKSFKRP 142


>sp|Q8BQ48|K1731_MOUSE Leucine-rich repeat-containing protein KIAA1731
            OS=Mus musculus GN=Kiaa1731 PE=2 SV=3
          Length = 2412

 Score = 32.3 bits (72), Expect = 0.76
 Identities = 19/46 (41%), Positives = 21/46 (45%), Gaps = 8/46 (17%)
 Frame = -2

Query: 146  RTLTVEHTALLAQNHLPRLPHKLHGSV--------AAASSSFPRPC 33
            RTL + HTAL  QN+L   P  LH           A     FPRPC
Sbjct: 1389 RTLGLSHTALPQQNNLTAHPEHLHAQTNFFHSTEKAQEGLVFPRPC 1434


>sp|Q7SGG0|SRB8_NEUCR Mediator of RNA polymerase II transcription
            subunit 12 OS=Neurospora crassa GN=srb-8 PE=3 SV=1
          Length = 1789

 Score = 30.0 bits (66), Expect = 3.8
 Identities = 9/31 (29%), Positives = 21/31 (67%)
 Frame = +2

Query: 23   QDVNMDEEMRRKQQQQSHEAYEEDEEGGSGP 115
            Q     ++ +++QQQQ ++  ++ ++GG+GP
Sbjct: 1664 QQQQQSQQQQQQQQQQQYQLQQQQQQGGTGP 1694


>sp|Q8A0Y9|REX_BACTN Redox-sensing transcriptional repressor rex
           OS=Bacteroides thetaiotaomicron GN=rex PE=3 SV=1
          Length = 220

 Score = 30.0 bits (66), Expect = 3.8
 Identities = 28/110 (25%), Positives = 46/110 (41%), Gaps = 5/110 (4%)
 Frame = -2

Query: 389 IKQYGTQITIHAQKSYTSTSSKPNGTP-----SSLKMTDEH*LCPWDVSKAVFAARQAIK 225
           +K +G +I        T   +  NG P       LK  +E+     DV   V      I 
Sbjct: 113 LKHFGLEIVAAFDVDPTLVGTNLNGIPIYHSDDFLKKMEEY-----DVQIGVLTVPIEIA 167

Query: 224 RNLFLTPVEGGELLKWNFNPTWTFISRTLTVEHTALLAQNHLPRLPHKLH 75
           + +    V+GG    WNF P    +   + V++T+L A  HL  + ++L+
Sbjct: 168 QCITDMMVDGGIKAVWNFTPFRIRVPEDIVVQNTSLYA--HLAVMFNRLN 215
tr_hit_id A9PG12
Definition tr|A9PG12|A9PG12_POPTR Putative uncharacterized protein OS=Populus trichocarpa
Align length 47
Score (bit) 73.6
E-value 5.0e-12
Report 
BLASTX 2.2.19 [Nov-02-2008]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= DK960408|Adiantum capillus-veneris mRNA, clone:
TST39A01NGRL0007_F10, 5'
         (414 letters)

Database: uniprot_trembl.fasta 
           7,341,751 sequences; 2,391,615,440 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

tr|A9PG12|A9PG12_POPTR Putative uncharacterized protein OS=Popul...    74   5e-12
tr|A7PKE8|A7PKE8_VITVI Chromosome chr15 scaffold_19, whole genom...    71   3e-11
tr|Q9ZWK3|Q9ZWK3_SALGI DnaJ homolog OS=Salix gilgiana GN=SGJ3 PE...    70   5e-11
tr|B4FJC3|B4FJC3_MAIZE Putative uncharacterized protein OS=Zea m...    70   5e-11
tr|Q0GLI7|Q0GLI7_ALLPO Molecular chaperone DjA2 OS=Allium porrum...    69   9e-11
tr|Q39812|Q39812_SOYBN Glycine max clone GMFP1 isoprenylated pro...    69   1e-10
tr|Q0PMD7|Q0PMD7_WHEAT J-domain protein OS=Triticum aestivum GN=...    69   2e-10
tr|Q949C1|Q949C1_ORYSA DnaJ-like protein OS=Oryza sativa GN=W930...    67   3e-10
tr|Q6H6G8|Q6H6G8_ORYSJ Putative DnaJ-like protein MsJ1 OS=Oryza ...    67   3e-10
tr|Q6F3B0|Q6F3B0_ORYSJ Os03g0787300 protein OS=Oryza sativa subs...    67   3e-10
tr|Q5NKI6|Q5NKI6_ORYSJ Putative DnaJ protein (Fragment) OS=Oryza...    67   3e-10
tr|Q0DYZ8|Q0DYZ8_ORYSJ Os02g0656500 protein OS=Oryza sativa subs...    67   3e-10
tr|B8AG47|B8AG47_ORYSI Putative uncharacterized protein OS=Oryza...    67   3e-10
tr|A9TW48|A9TW48_PHYPA Predicted protein OS=Physcomitrella paten...    67   3e-10
tr|A2XMP7|A2XMP7_ORYSI Putative uncharacterized protein OS=Oryza...    67   3e-10
tr|A9RML5|A9RML5_PHYPA Predicted protein OS=Physcomitrella paten...    67   4e-10
tr|A9T6M4|A9T6M4_PHYPA Predicted protein OS=Physcomitrella paten...    67   6e-10
tr|A9NK86|A9NK86_PICSI Putative uncharacterized protein OS=Picea...    67   6e-10
tr|Q9S7X7|Q9S7X7_SALGI DnaJ homolog protein OS=Salix gilgiana PE...    66   8e-10
tr|B7FGC0|B7FGC0_MEDTR Putative uncharacterized protein OS=Medic...    66   1e-09
tr|A9SP23|A9SP23_PHYPA Predicted protein OS=Physcomitrella paten...    65   2e-09
tr|Q9ZSZ6|Q9ZSZ6_HEVBR DnaJ protein OS=Hevea brasiliensis PE=2 SV=1    64   3e-09
tr|Q7X6U9|Q7X6U9_ORYSJ OSJNBb0034G17.1 protein (Putative unchara...    64   3e-09
tr|Q0JB88|Q0JB88_ORYSJ Os04g0549600 protein OS=Oryza sativa subs...    64   3e-09
tr|Q01ID9|Q01ID9_ORYSA OSIGBa0134H18.3 protein OS=Oryza sativa G...    64   3e-09
tr|A2XW64|A2XW64_ORYSI Putative uncharacterized protein OS=Oryza...    64   3e-09
tr|Q9FSF2|Q9FSF2_TOBAC Putative DNAJ protein OS=Nicotiana tabacu...    64   5e-09
tr|B0FFN7|B0FFN7_ORYSJ DnaJ family heat shock protein OS=Oryza s...    62   1e-08
tr|Q9M554|Q9M554_EUPES DnaJ protein OS=Euphorbia esula PE=2 SV=1       62   1e-08
tr|Q8GT37|Q8GT37_SOLTU Tuber-induction protein (Fragment) OS=Sol...    62   1e-08

>tr|A9PG12|A9PG12_POPTR Putative uncharacterized protein OS=Populus
           trichocarpa PE=2 SV=1
          Length = 422

 Score = 73.6 bits (179), Expect = 5e-12
 Identities = 35/47 (74%), Positives = 40/47 (85%), Gaps = 2/47 (4%)
 Frame = +2

Query: 2   ECEETILQDVNMDEEMRRKQQQQSHEAYEEDEE--GGSGPRVQCAQQ 136
           ECEET L DVN++EEMRRKQQQQ+ EAY+ED+E  GG G RVQCAQQ
Sbjct: 376 ECEETTLHDVNIEEEMRRKQQQQAQEAYDEDDEMHGGGGQRVQCAQQ 422


>tr|A7PKE8|A7PKE8_VITVI Chromosome chr15 scaffold_19, whole genome
           shotgun sequence OS=Vitis vinifera GN=GSVIVT00019136001
           PE=4 SV=1
          Length = 419

 Score = 70.9 bits (172), Expect = 3e-11
 Identities = 32/45 (71%), Positives = 37/45 (82%)
 Frame = +2

Query: 2   ECEETILQDVNMDEEMRRKQQQQSHEAYEEDEEGGSGPRVQCAQQ 136
           E EET L DVN++EEMRRKQQQQ HEAY+ED++    PRVQCAQQ
Sbjct: 375 EAEETTLYDVNIEEEMRRKQQQQQHEAYDEDDDDFGAPRVQCAQQ 419


>tr|Q9ZWK3|Q9ZWK3_SALGI DnaJ homolog OS=Salix gilgiana GN=SGJ3 PE=2
           SV=1
          Length = 420

 Score = 70.1 bits (170), Expect = 5e-11
 Identities = 34/46 (73%), Positives = 38/46 (82%), Gaps = 1/46 (2%)
 Frame = +2

Query: 2   ECEETILQDVNMDEEMRRKQQQQSHEAYEEDEE-GGSGPRVQCAQQ 136
           ECEET L DVN+DEEMRRKQQQQ+ EAY+ED+E  G   RVQCAQQ
Sbjct: 375 ECEETTLHDVNIDEEMRRKQQQQAQEAYDEDDEMPGGAQRVQCAQQ 420


>tr|B4FJC3|B4FJC3_MAIZE Putative uncharacterized protein OS=Zea mays
           PE=2 SV=1
          Length = 422

 Score = 70.1 bits (170), Expect = 5e-11
 Identities = 31/45 (68%), Positives = 38/45 (84%)
 Frame = +2

Query: 2   ECEETILQDVNMDEEMRRKQQQQSHEAYEEDEEGGSGPRVQCAQQ 136
           +CEET L DVN++EEMRR+QQQ+  EAY+EDEE  + PRVQCAQQ
Sbjct: 378 QCEETTLHDVNIEEEMRRRQQQKKQEAYDEDEEEDAQPRVQCAQQ 422


>tr|Q0GLI7|Q0GLI7_ALLPO Molecular chaperone DjA2 OS=Allium porrum
           PE=2 SV=1
          Length = 418

 Score = 69.3 bits (168), Expect = 9e-11
 Identities = 32/46 (69%), Positives = 38/46 (82%), Gaps = 1/46 (2%)
 Frame = +2

Query: 2   ECEETILQDVNMDEEMRRKQQQQSHEAYEEDEEG-GSGPRVQCAQQ 136
           ECEET + DVN++EEMRRKQ Q + EAY+ED+EG G G RVQCAQQ
Sbjct: 373 ECEETTMHDVNIEEEMRRKQHQHAQEAYDEDDEGHGGGQRVQCAQQ 418


>tr|Q39812|Q39812_SOYBN Glycine max clone GMFP1 isoprenylated
           protein (Fragment) OS=Glycine max PE=2 SV=1
          Length = 86

 Score = 68.9 bits (167), Expect = 1e-10
 Identities = 32/45 (71%), Positives = 36/45 (80%)
 Frame = +2

Query: 2   ECEETILQDVNMDEEMRRKQQQQSHEAYEEDEEGGSGPRVQCAQQ 136
           +CEET L DVN  EEMRRKQQQQ  EAY+ED++  SG RVQCAQQ
Sbjct: 42  DCEETTLHDVNFKEEMRRKQQQQYREAYDEDDDEPSGQRVQCAQQ 86


>tr|Q0PMD7|Q0PMD7_WHEAT J-domain protein OS=Triticum aestivum GN=J3
           PE=2 SV=1
          Length = 420

 Score = 68.6 bits (166), Expect = 2e-10
 Identities = 31/47 (65%), Positives = 40/47 (85%), Gaps = 2/47 (4%)
 Frame = +2

Query: 2   ECEETILQDVNMDEEMRRKQQQQSHEAYEEDEE--GGSGPRVQCAQQ 136
           ECEET+  D++++EEMRR+QQQQ+ EAY+EDE+  GG G RVQCAQQ
Sbjct: 374 ECEETMAYDIDIEEEMRRRQQQQAQEAYDEDEDMPGGGGQRVQCAQQ 420


>tr|Q949C1|Q949C1_ORYSA DnaJ-like protein OS=Oryza sativa
           GN=W930ERIPDK PE=4 SV=1
          Length = 420

 Score = 67.4 bits (163), Expect = 3e-10
 Identities = 30/47 (63%), Positives = 39/47 (82%), Gaps = 2/47 (4%)
 Frame = +2

Query: 2   ECEETILQDVNMDEEMRRKQQQQSHEAYEE--DEEGGSGPRVQCAQQ 136
           +CEET + DVN++EEMRR+QQ +  EAY+E  DE+ G+GPRVQCAQQ
Sbjct: 374 QCEETTMHDVNIEEEMRRRQQHRRQEAYDEDDDEDAGAGPRVQCAQQ 420


>tr|Q6H6G8|Q6H6G8_ORYSJ Putative DnaJ-like protein MsJ1 OS=Oryza
           sativa subsp. japonica GN=P0519E06.27 PE=4 SV=1
          Length = 416

 Score = 67.4 bits (163), Expect = 3e-10
 Identities = 30/47 (63%), Positives = 39/47 (82%), Gaps = 2/47 (4%)
 Frame = +2

Query: 2   ECEETILQDVNMDEEMRRKQQQQSHEAYEE--DEEGGSGPRVQCAQQ 136
           +CEET + DVN++EEMRR+QQ +  EAY+E  DE+ G+GPRVQCAQQ
Sbjct: 370 QCEETTMHDVNIEEEMRRRQQHRRQEAYDEDDDEDAGAGPRVQCAQQ 416


>tr|Q6F3B0|Q6F3B0_ORYSJ Os03g0787300 protein OS=Oryza sativa subsp.
           japonica GN=OSJNBb0024J04.9 PE=2 SV=1
          Length = 417

 Score = 67.4 bits (163), Expect = 3e-10
 Identities = 32/47 (68%), Positives = 38/47 (80%), Gaps = 2/47 (4%)
 Frame = +2

Query: 2   ECEETILQDVNMDEEMRRKQQQQSHEAYEEDEE--GGSGPRVQCAQQ 136
           ECEET+  DVN++EEMRR+QQQQ  EAY+EDE+  GG   RVQCAQQ
Sbjct: 371 ECEETMPYDVNIEEEMRRRQQQQQQEAYDEDEDMHGGGAQRVQCAQQ 417