| H00301 | |
| H番号 | H00301 |
| 名称 | クレブシェラ感染症 |
| 概要 | Klebsiella is a gram-negative bacterium of Enterobacteriaceae, which has emerged as an important cause of hospital-acquired infections. Infections caused by extended-spectrum beta-lactamase (ESBL)-producing pathogens, particularly Klebsiella pneumoniae, are increasing. ESBL are plasmid-mediated enzymes and these plasmids also carry resistance genes to other antibiotics including aminoglycosides, chloramphenicol, sulfonamides, trimethoprim, and tetracycline. Thus, Gram-negative bacilli containing these plasmids are multidrug-resistant. Klebsiella pneumoniae can cause sepsis, conjunctivitis, urinary tract infections, and surgical site infections. Bloodstream infections with Klebsiella markedly increase the rates of treatment failure and death. |
| カテゴリ | 細菌感染症 |
| ネットワーク | - |
| 病因遺伝子 | - |
| 病原体 | Klebsiella pneumoniae [GN:kpn kpu kpm kpp kph kpz kpv kpw kpy kpg kpc kpq kpt kpr kpa kps kpx kpb kpnk] Klebsiella oxytoca [GN:koe kok] Klebsiella quasipneumoniae [GN:kqu] Klebsiella aerogenes [GN:ear] Klebsiella quasivariicola [GN:kqv] Klebsiella sp. WCHKl090001 [GN:klw] Klebsiella pasteurii [GN:kpas] |
| 環境要因 | - |
| 発癌物質 | - |
| 治療薬 | - |
| コメント | - |
| リンク | ICD-11: CA40.03 ICD-10: A49.8 B96.1 J15.0 MeSH: D007710 |
| 文献 | PMID:21653305 著者 Gupta N, Limbago BM, Patel JB, Kallen AJ タイトル Carbapenem-resistant Enterobacteriaceae: epidemiology and prevention. 雑誌 Clin Infect Dis 53:60-7 (2011) DOI:10.1093/cid/cir202 PMID:13679928 著者 Gupta A, Ampofo K, Rubenstein D, Saiman L タイトル Extended spectrum beta lactamase-producing Klebsiella pneumoniae infections: a review of the literature. 雑誌 J Perinatol 23:439-43 (2003) DOI:10.1038/sj.jp.7210973 PMID:16436702 著者 Tumbarello M, Spanu T, Sanguinetti M, Citton R, Montuori E, Leone F, Fadda G, Cauda R タイトル Bloodstream infections caused by extended-spectrum-beta-lactamase-producing Klebsiella pneumoniae: risk factors, molecular epidemiology, and clinical outcome. 雑誌 Antimicrob Agents Chemother 50:498-504 (2006) DOI:10.1128/AAC.50.2.498-504.2006 PMID:15711657 著者 Panhotra BR, Saxena AK, Al-Ghamdi AM タイトル Extended-spectrum beta-lactamase-producing Klebsiella pneumoniae hospital acquired bacteremia. Risk factors and clinical outcome. 雑誌 Saudi Med J 25:1871-6 (2004) |