| H00317 | |
| H番号 | H00317 |
| 名称 | 類鼻疽 |
| 概要 | Melioidosis (MD) is an infection caused by the gram-negative soil-dwelling bacillus Burkholderia pseudomallei. It predominantly affects people in regular contact with soil and water and is endemic in areas of Southeast Asia and Northern Australia. There are many possible disease manifestations including melioidosis septic shock, pneumonia, and hepatic and splenic abscesses. |
| カテゴリ | 細菌感染症 |
| ネットワーク | - |
| 病因遺伝子 | TLR5 (resistance) [HSA:7100] [KO:K10168] |
| 病原体 | Burkholderia pseudomallei [GN:bps bpm bpl bpd bpr bpse bpz bpq] |
| 環境要因 | - |
| 発癌物質 | - |
| 治療薬 | - |
| コメント | - |
| リンク | ICD-11: 1C42 ICD-10: A24.1 A24.2 A24.3 A24.4 MeSH: D008554 OMIM: 615557 |
| 文献 | PMID:21558159 著者 Limmathurotsakul D, Peacock SJ タイトル Melioidosis: a clinical overview. 雑誌 Br Med Bull 99:125-39 (2011) DOI:10.1093/bmb/ldr007 PMID:16541135 著者 Wiersinga WJ, van der Poll T, White NJ, Day NP, Peacock SJ タイトル Melioidosis: insights into the pathogenicity of Burkholderia pseudomallei. 雑誌 Nat Rev Microbiol 4:272-82 (2006) DOI:10.1038/nrmicro1385 PMID:23447684 (TLR5) 著者 West TE, Chantratita N, Chierakul W, Limmathurotsakul D, Wuthiekanun V, Myers ND, Emond MJ, Wurfel MM, Hawn TR, Peacock SJ, Skerrett SJ タイトル Impaired TLR5 functionality is associated with survival in melioidosis. 雑誌 J Immunol 190:3373-9 (2013) DOI:10.4049/jimmunol.1202974 |