| H00346 | |
| H番号 | H00346 |
| 名称 | 外因性アレルギー性肺胞炎; 過敏性肺炎 |
| 概要 | Extrinsic allergic alveolitis (EAA), also known as hypersensitivity pneumonitis, is caused by repeated inhalation of mainly organic antigens by sensitized subjects. This induces a hypersensitivity response in the distal bronchioles and alveoli and subjects may present clinically with a variety of symptoms. EAA is caused by a wide variety of antigens including bacteria, organic materials, fungal spores, and chemicals. Of the various EAA syndromes, Farmer's lung and Bird fancier's disease are the commonest forms that have been studied. EAA is a complex dynamic clinical syndrome where clinical expression depends on the frequency and amount of contact with antigen and host susceptibility. The manifestations and symptoms can be complicated by self-regulatory measures performed by those affected individuals to reduce antigen exposure. There are many individuals with a positive antibody reaction who remain asymptomatic. EAA traditionally has been described as occurring in a state of acute, subacute, and chronic form. |
| カテゴリ | 免疫系疾患 |
| ネットワーク | - |
| 病因遺伝子 | - |
| 病原体 | - |
| 環境要因 | - |
| 発癌物質 | - |
| 治療薬 | - |
| コメント | - |
| リンク | ICD-11: CA70 ICD-10: J67 MeSH: D000542 MedlinePlus: 000109 |
| 文献 | PMID:16635083 著者 Ismail T, McSharry C, Boyd G タイトル Extrinsic allergic alveolitis. 雑誌 Respirology 11:262-8 (2006) DOI:10.1111/j.1440-1843.2006.00839.x |