| H00358 | |
| H番号 | H00358 |
| 名称 | シャーガス病 |
| 概要 | Chagas disease, also known as American trypanosomiasis, is caused by infection with protozoan parasite Trypanosoma cruzi. The infection is transmitted by hematophagous reduviid insect vectors through fecal contamination. The majority of infected individuals live in Latin American countries. Chagas disease is characterized by an acute phase followed by a chronic phase, with sustained inflammation that causes cardiomyopathy, digestive disorders, and neuropathies. |
| カテゴリ | 寄生虫感染症 疾患パスウェイ hsa05142 シャーガス病 |
| ネットワーク | - |
| 病因遺伝子 | - |
| 病原体 | Trypanosoma cruzi [GN:tcr] |
| 環境要因 | - |
| 発癌物質 | - |
| 治療薬 | - |
| コメント | Vector: Rhodnius prolixus (Reduviid bug) |
| リンク | ICD-11: 1F53 ICD-10: B57 MeSH: D014355 MedlinePlus: 001372 |
| 文献 | PMID:26222561 著者 Bern C タイトル Chagas' Disease. 雑誌 N Engl J Med 373:456-66 (2015) DOI:10.1056/NEJMra1410150 PMID:31006555 著者 Guarner J タイトル Chagas disease as example of a reemerging parasite. 雑誌 Semin Diagn Pathol 36:164-169 (2019) DOI:10.1053/j.semdp.2019.04.008 |