| H00721 | |
| H番号 | H00721 |
| 名称 | Pyogenic bacterial infections, recurrent, due to MYD88 deficiency |
| 概要 | Autosomal recessive MyD88 deficiency predisposes affected patients to recurrent pyogenic bacterial infections, including invasive pneumococcal disease. The patients are resistant to other microbes. |
| カテゴリ | 免疫系疾患 |
| ネットワーク | - |
| 病因遺伝子 | MYD88 [HSA:4615] [KO:K04729] |
| 病原体 | - |
| 環境要因 | - |
| 発癌物質 | - |
| 治療薬 | - |
| コメント | - |
| リンク | ICD-11: 4A00.2 MeSH: C567379 OMIM: 612260 |
| 文献 | PMID:18669862 著者 von Bernuth H, Picard C, Jin Z, Pankla R, Xiao H, Ku CL, Chrabieh M, Mustapha IB, Ghandil P, Camcioglu Y, Vasconcelos J, Sirvent N, Guedes M, Vitor AB, Herrero-Mata MJ, Arostegui JI, Rodrigo C, Alsina L, Ruiz-Ortiz E, Juan M, Fortuny C, Yague J, Anton J, Pascal M, Chang HH, Janniere L, Rose Y, Garty BZ, Chapel H, Issekutz A, Marodi L, Rodriguez-Gallego C, Banchereau J, Abel L, Li X, Chaussabel D, Puel A, Casanova JL タイトル Pyogenic bacterial infections in humans with MyD88 deficiency. 雑誌 Science 321:691-6 (2008) DOI:10.1126/science.1158298 PMID:21734245 著者 Picard C, Casanova JL, Puel A タイトル Infectious diseases in patients with IRAK-4, MyD88, NEMO, or IkappaBalpha deficiency. 雑誌 Clin Microbiol Rev 24:490-7 (2011) DOI:10.1128/CMR.00001-11 PMID:20236864 著者 Bousfiha A, Picard C, Boisson-Dupuis S, Zhang SY, Bustamante J, Puel A, Jouanguy E, Ailal F, El-Baghdadi J, Abel L, Casanova JL タイトル Primary immunodeficiencies of protective immunity to primary infections. 雑誌 Clin Immunol 135:204-9 (2010) DOI:10.1016/j.clim.2010.02.001 |