| H00829 | |
| H番号 | H00829 |
| 名称 | 多発性家族性毛包上皮腫 |
| 概要 | Multiple familial trichoepithelioma (MFT) is a benign epidermal tumor characterized by grouped nodules and papules on the face. The lesions are derived from immature hair follicles. It is inherited in autosomal dominant fashion and is related to Brooke-Spiegler syndrome and Familial cylindromatosis. |
| カテゴリ | 新生物 |
| ネットワーク | - |
| 病因遺伝子 | CYLD [HSA:1540] [KO:K08601] |
| 病原体 | - |
| 環境要因 | - |
| 発癌物質 | - |
| 治療薬 | - |
| コメント | - |
| リンク | ICD-11: 2F22 ICD-10: D23.3 MeSH: C536552 OMIM: 601606 |
| 文献 | PMID:18355210 著者 Oranje AP, Halley D, den Hollander JC, Teepe RG, van de Graaf R, van den Ouweland A, Wagner A タイトル Multiple familial trichoepithelioma and familial cylindroma: one cause! 雑誌 J Eur Acad Dermatol Venereol 22:1395-6 (2008) DOI:10.1111/j.1468-3083.2008.02648.x PMID:21389835 (CYLD) 著者 Kazakov DV, Vanecek T, Zelger B, Carlson JA, Spagnolo DV, Schaller J, Nemcova J, Kacerovska D, Vazmitel M, Sangueza M, Emberger M, Belousova I, Fernandez-Figueraz MT, Kempf W, Meyer DR, Rutten A, Baltaci M, Michal M タイトル Multiple (familial) trichoepitheliomas: a clinicopathological and molecular biological study, including CYLD and PTCH gene analysis, of a series of 16 patients. 雑誌 Am J Dermatopathol 33:251-65 (2011) DOI:10.1097/DAD.0b013e3181f7d373 |