| H00864 | |
| H番号 | H00864 |
| 名称 | 抜毛癖 |
| 概要 | Trichotillomania (TTM) is a chronic behavioral disorder characterized by the irresistible urge to pull out one's hair, resulting in noticeable hair loss. Mutations in SLITRK1 are found in patients with TTM. |
| カテゴリ | 精神及び行動の障害 |
| ネットワーク | - |
| 病因遺伝子 | SLITRK1 [HSA:114798] [KO:K25832] |
| 病原体 | - |
| 環境要因 | - |
| 発癌物質 | - |
| 治療薬 | - |
| コメント | Mutations in SLITRK1 are also found in patients with Tourette syndrome. [DS:H00862] |
| リンク | ICD-11: 6B25.0 ICD-10: F63.3 MeSH: D014256 OMIM: 613229 |
| 文献 | PMID:17003809 著者 Zuchner S, Cuccaro ML, Tran-Viet KN, Cope H, Krishnan RR, Pericak-Vance MA, Wright HH, Ashley-Koch A タイトル SLITRK1 mutations in trichotillomania. 雑誌 Mol Psychiatry 11:887-9 (2006) DOI:10.1038/sj.mp.4001865 PMID:18794888 著者 Katayama K, Yamada K, Ornthanalai VG, Inoue T, Ota M, Murphy NP, Aruga J タイトル Slitrk1-deficient mice display elevated anxiety-like behavior and noradrenergic abnormalities. 雑誌 Mol Psychiatry 15:177-84 (2010) DOI:10.1038/mp.2008.97 |