| H00947 | |
| H番号 | H00947 |
| 名称 | 毛母腫 |
| 概要 | Pilomatricoma is a benign cutaneous tumor of follicular structures. It occurs either in isolation or in conjunction with other symptoms such as myotonic dystrophy and Rubenstein-Taybi syndrome. The histologic appearance of the tumor is characterized by cells resembling those of the hair follicle matrix and sometimes show differentiation toward the follicular infundibulum and surrounding sheath. |
| カテゴリ | 新生物 |
| ネットワーク | - |
| 病因遺伝子 | CTNNB1 [HSA:1499] [KO:K02105] |
| 病原体 | - |
| 環境要因 | - |
| 発癌物質 | - |
| 治療薬 | - |
| コメント | - |
| リンク | ICD-11: 2F22 ICD-10: D23 MeSH: D018296 OMIM: 132600 |
| 文献 | PMID:11708952 著者 Tsao H. タイトル Genetics of nonmelanoma skin cancer. 雑誌 Arch Dermatol 137:1486-92 (2001) DOI:10.1001/archderm.137.11.1486 PMID:10192393 著者 Chan EF, Gat U, McNiff JM, Fuchs E タイトル A common human skin tumour is caused by activating mutations in beta-catenin. 雑誌 Nat Genet 21:410-3 (1999) DOI:10.1038/7747 PMID:15606674 著者 Lazar AJ, Calonje E, Grayson W, Dei Tos AP, Mihm MC Jr, Redston M, McKee PH タイトル Pilomatrix carcinomas contain mutations in CTNNB1, the gene encoding beta-catenin. 雑誌 J Cutan Pathol 32:148-57 (2005) DOI:10.1111/j.0303-6987.2005.00267.x |