| H01039 | |
| H番号 | H01039 |
| 名称 | 卵巣過刺激症候群 |
| 概要 | Ovarian hyperstimulation syndrome (OHSS) is typically an iatrogenic complication of ovulation induction (OI) occurring during the luteal phase or early pregnancy. OHSS is characterised by a cystic enlargement of the ovaries and an acute fluid shift from the intravascular to the third space, which may result in ascites, pleural infusions, pericardial infusion, and even generalized edema. Majority of OHSS cases have been associated with the use of gonadotrophins for OI in anovulatory women or for ovarian stimulation (OS) in the context of assisted reproductive technology (ART). Recurrent cases and familial occurrence of OHSS have been described, and different mutations in the follicle-stimulating hormone receptor (FSHr) have been reported in these cases. Polycystic ovarian syndrome (PCOS) appears to be the major predisposing factor for OHSS in a large number of studies. |
| カテゴリ | 生殖器系疾患 |
| ネットワーク | - |
| 病因遺伝子 | FSHR [HSA:2492] [KO:K04247] |
| 病原体 | - |
| 環境要因 | - |
| 発癌物質 | - |
| 治療薬 | - |
| コメント | - |
| リンク | ICD-11: GA32.0 ICD-10: N98.1 MeSH: D016471 OMIM: 608115 |
| 文献 | PMID:20977119 著者 Kasum M タイトル New insights in mechanisms for development of ovarian hyperstimulation syndrome. 雑誌 Coll Antropol 34:1139-43 (2010) PMID:19632900 著者 Vloeberghs V, Peeraer K, Pexsters A, D'Hooghe T タイトル Ovarian hyperstimulation syndrome and complications of ART. 雑誌 Best Pract Res Clin Obstet Gynaecol 23:691-709 (2009) DOI:10.1016/j.bpobgyn.2009.02.006 PMID:20416867 著者 Humaidan P, Quartarolo J, Papanikolaou EG タイトル Preventing ovarian hyperstimulation syndrome: guidance for the clinician. 雑誌 Fertil Steril 94:389-400 (2010) DOI:10.1016/j.fertnstert.2010.03.028 PMID:17055817 タイトル Ovarian hyperstimulation syndrome. 雑誌 Fertil Steril 86:S178-83 (2006) DOI:10.1016/j.fertnstert.2006.08.021 |