| H01175 | |
| H番号 | H01175 |
| 名称 | ブドウ球菌感染症 |
| 概要 | Staphylococci are widespread as commensals of humans and animals where they colonize the skin or mucous membranes. Firstly, Staphylococcus lugdunensis is a most unusual coagulase-negative staphylococcus found on the human skin. It can cause infections at many sites including superficial skin infections, bacteremia, endocarditis, osteomyelitis, and breast abscess. Endocarditis caused by S. lugdunensis can lead to substantial morbidity and mortality. Secondly, Staphylococcus haemolyticus, found among the normal skin flora, is commonly isolated from the axillae, perineum, and inguinal areas of humans and causes septicemia, peritonitis, otitis, and urinary tract infections. S. haemolyticus is notorious for its multidrug resistance and historically early acquisition of resistance to methicillin and glycopeptide antibiotics. Finally, Staphylococcus pseudintermedius is an important opportunistic pathogen of dogs and cats. S. pseudintermedius colonization is very uncommon in humans. It is rarely isolated from human dog-bite wounds. The infection has been associated with wide range of symptoms such as bacteremia, a brain abscess, and pneumonia. |
| カテゴリ | 細菌感染症 |
| ネットワーク | - |
| 病因遺伝子 | - |
| 病原体 | Staphylococcus lugdunensis [GN:slg sln] Staphylococcus haemolyticus [GN:sha] Staphylococcus pseudintermedius |
| 環境要因 | - |
| 発癌物質 | - |
| 治療薬 | - |
| コメント | Treatment was most commonly initiated with vancomycin and narrowed as antibiotic susceptibilities allowed. Methicillin resistance has been reported. |
| リンク | ICD-11: 1A10 ICD-10: A41.1 MeSH: D013203 |
| 文献 | PMID:21886051 著者 Klotchko A, Wallace MR, Licitra C, Sieger B タイトル Staphylococcus lugdunensis: an emerging pathogen. 雑誌 South Med J 104:509-14 (2011) DOI:10.1097/SMJ.0b013e31821e91b1 PMID:21195974 著者 Liu PY, Huang YF, Tang CW, Chen YY, Hsieh KS, Ger LP, Chen YS, Liu YC タイトル Staphylococcus lugdunensis infective endocarditis: a literature review and analysis of risk factors. 雑誌 J Microbiol Immunol Infect 43:478-84 (2010) DOI:10.1016/S1684-1182(10)60074-6 PMID:20434383 著者 Chopra A, Gulati D, Woldenberg N, Singh M タイトル Intracardiac lead endocarditis due to Staphylococcus lugdunensis. 雑誌 Int J Infect Dis 14 Suppl 3:e291-3 (2010) DOI:10.1016/j.ijid.2009.12.008 PMID:19447659 著者 Pada S, Lye DC, Leo YS, Barkham T タイトル Utility of 16S ribosomal DNA sequencing in the diagnosis of Staphylococcus lugdunensis native valve infective endocarditis: case report and literature review. 雑誌 Int J Infect Dis 13:e511-3 (2009) DOI:10.1016/j.ijid.2009.02.019 PMID:21930571 著者 van Duijkeren E, Catry B, Greko C, Moreno MA, Pomba MC, Pyorala S, Ruzauskas M, Sanders P, Threlfall EJ, Torren-Edo J, Torneke K タイトル Review on methicillin-resistant Staphylococcus pseudintermedius. 雑誌 J Antimicrob Chemother 66:2705-14 (2011) DOI:10.1093/jac/dkr367 PMID:20178486 著者 Fitzgerald JR タイトル The Staphylococcus intermedius group of bacterial pathogens: species re-classification, pathogenesis and the emergence of meticillin resistance. 雑誌 Vet Dermatol 20:490-5 (2009) DOI:10.1111/j.1365-3164.2009.00828.x PMID:19246166 著者 Weese JS, van Duijkeren E タイトル Methicillin-resistant Staphylococcus aureus and Staphylococcus pseudintermedius in veterinary medicine. 雑誌 Vet Microbiol 140:418-29 (2010) DOI:10.1016/j.vetmic.2009.01.039 PMID:16237012 著者 Takeuchi F, Watanabe S, Baba T, Yuzawa H, Ito T, Morimoto Y, Kuroda M, Cui L, Takahashi M, Ankai A, Baba S, Fukui S, Lee JC, Hiramatsu K. タイトル Whole-genome sequencing of staphylococcus haemolyticus uncovers the extreme plasticity of its genome and the evolution of human-colonizing staphylococcal species. 雑誌 J Bacteriol 187:7292-308 (2005) DOI:10.1128/JB.187.21.7292-7308.2005 |