| H01206 | |
| H番号 | H01206 |
| 名称 | プラスミノーゲン欠損症 |
| 概要 | Plasminogen deficiency is characterized by decreased serum plasminogen activity. Two forms of the disorder are distinguished. Type 1, also called hypoplasminogenemia, is associated with pseudomembrane disease. Ligneous conjunctivitis is the most common of the clinical syndromes associated with plasminogen deficiency, although numerous other organs have been reported to be affected. Type 2, also known as dysplasminogenemia, is characterized by normal, or slightly reduced antigen levels, and absence of clinical manifestations. |
| カテゴリ | 血液疾患 |
| ネットワーク | nt06514(H01206) Coagulation cascade |
| 病因遺伝子 | PLG [HSA:5340] [KO:K01315] |
| 病原体 | - |
| 環境要因 | - |
| 発癌物質 | - |
| 治療薬 | - |
| コメント | - |
| リンク | ICD-11: 3B50.Y ICD-10: L90.5 MeSH: C566897 OMIM: 217090 |
| 文献 | PMID:19141167 著者 Mehta R, Shapiro AD タイトル Plasminogen deficiency. 雑誌 Haemophilia 14:1261-8 (2008) DOI:10.1111/j.1365-2516.2008.01825.x PMID:17900274 著者 Schuster V, Hugle B, Tefs K タイトル Plasminogen deficiency. 雑誌 J Thromb Haemost 5:2315-22 (2007) DOI:10.1111/j.1538-7836.2007.02776.x |