| H01320 | |
| H番号 | H01320 |
| 名称 | 流行性角結膜炎 |
| 概要 | Epidemic keratoconjunctivitis (EKC) is a highly contagious and severe form of eye disease caused by human adenoviruses (HAdVs). There are two well-defined adenoviral keratoconjunctivitis clinical syndromes: EKC and pharyngoconjunctival fever (PCF) [DS:H01420], which are caused by different HAdV serotypes. HAdV-8, HAdV-19, and HAdV-37 are common causative agents of EKC. In addition to these above-mentioned types, HAdV-3, HAdV-4, HAdV-7, HAdV-9, HAdV-15, HAdV-53, and HAdV-54 have also been identified as causative agents of EKC. However, HAV-8 is responsible for the highest number of EKC cases worldwide and is associated with severe clinical manifestations. EKC patients may complain about influenza-like symptoms, including fever, malaise, respiratory symptoms, nausea, vomiting, diarrhea, and myalgia. The incubation period is 2-14 days, and the person may remain infectious for 10-14 days after the onset of the symptoms. Symptoms tend to last for 7-21 days. |
| カテゴリ | ウイルス感染症 |
| ネットワーク | - |
| 病因遺伝子 | - |
| 病原体 | Human mastadenovirus B [GN:T40100] Human mastadenovirus D [GN:T40102] Human mastadenovirus E [GN:T40101] Human adenovirus 8, 19, 37 |
| 環境要因 | - |
| 発癌物質 | - |
| 治療薬 | - |
| コメント | - |
| リンク | ICD-11: 1D84.0 ICD-10: B30.0 MeSH: D007639 |
| 文献 | PMID:25464969 著者 Adhikary AK, Banik U タイトル Human adenovirus type 8: the major agent of epidemic keratoconjunctivitis (EKC). 雑誌 J Clin Virol 61:477-86 (2014) DOI:10.1016/j.jcv.2014.10.015 PMID:24678403 著者 Ghebremedhin B タイトル Human adenovirus: Viral pathogen with increasing importance. 雑誌 Eur J Microbiol Immunol (Bp) 4:26-33 (2014) DOI:10.1556/EuJMI.4.2014.1.2 |