| H01361 | |
| H番号 | H01361 |
| 名称 | 好酸球性食道炎 |
| 概要 | Eosinophilic esophagitis (EoE) is a chronic immune and antigen-mediated clinicopathologic disease that is characterized by eosinophil infiltration into the esophageal epithelium and results in esophageal fibrosis and dysfunction. Several factors contribute to the development of EoE, including genetic predisposition, history of allergies, and presence of environmental and food allergens. Recently, an association between a single nuclear polymorphism (SNP) in the gene encoding thymic stromal lymphopoietin (TSLP) or eotaxin-3 (CCL-26) and risk for EoE was found. |
| カテゴリ | 免疫系疾患 |
| ネットワーク | - |
| 病因遺伝子 | TSLP (polymorphism) [HSA:85480] [KO:K05436] CCL-26 (polymorphism) [HSA:10344] [KO:K21096] |
| 病原体 | - |
| 環境要因 | - |
| 発癌物質 | - |
| 治療薬 | - |
| コメント | - |
| リンク | ICD-11: DA24.1 MeSH: D057765 |
| 文献 | PMID:22313241 著者 Straumann A, Aceves SS, Blanchard C, Collins MH, Furuta GT, Hirano I, Schoepfer AM, Simon D, Simon HU タイトル Pediatric and adult eosinophilic esophagitis: similarities and differences. 雑誌 Allergy 67:477-90 (2012) DOI:10.1111/j.1398-9995.2012.02787.x PMID:21228772 著者 Mulder DJ, Justinich CJ タイトル Understanding eosinophilic esophagitis: the cellular and molecular mechanisms of an emerging disease. 雑誌 Mucosal Immunol 4:139-47 (2011) DOI:10.1038/mi.2010.88 PMID:17088129 著者 Blanchard C, Wang N, Rothenberg ME タイトル Eosinophilic esophagitis: pathogenesis, genetics, and therapy. 雑誌 J Allergy Clin Immunol 118:1054-9 (2006) DOI:10.1016/j.jaci.2006.07.038 PMID:24566295 著者 Merves J, Muir A, Modayur Chandramouleeswaran P, Cianferoni A, Wang ML, Spergel JM タイトル Eosinophilic esophagitis. 雑誌 Ann Allergy Asthma Immunol 112:397-403 (2014) DOI:10.1016/j.anai.2014.01.023 PMID:23130328 著者 Ridolo E, Montagni M, Olivieri E, Rogkakou A, De' Angelis GL, Canonica GW タイトル Eosinophilic esophagitis: which role for food and inhalant allergens? 雑誌 Asia Pac Allergy 2:237-41 (2012) DOI:10.5415/apallergy.2012.2.4.237 PMID:21991511 著者 Shahzad G, Mustacchia P, Frieri M タイトル Role of mucosal inflammation in eosinophilic esophagitis: review of the literature. 雑誌 ISRN Gastroenterol 2011:468073 (2011) DOI:10.5402/2011/468073 PMID:23001405 著者 Redd M, Schey R タイトル Eosinophilic esophagitis: current treatment. 雑誌 Dig Dis Sci 58:613-20 (2013) DOI:10.1007/s10620-012-2383-1 PMID:22034864 著者 Abonia JP, Rothenberg ME タイトル Eosinophilic esophagitis: rapidly advancing insights. 雑誌 Annu Rev Med 63:421-34 (2012) DOI:10.1146/annurev-med-041610-134138 |