| H01636 | |
| H番号 | H01636 |
| 名称 | 線維筋痛症; 線維筋痛症候群 |
| 概要 | Fibromyalgia is a common and chronic pain disorder that predominantly affects women. It belongs to the group of rheumatic disorders of the soft tissues, and is characterised by widespread chronic pain, cognitive and affective disturbances and fatigue. The etiology and pathogenesis of fibromyalgia is uncertain. Genetic studies suggest an association with polymorphisms in serotonergic, dopaminergic, and catecholaminergic pathways involved in pain transmission and modulation. The disease is likely expressed in the presence of environmental trigger, which lead to expression of multiple genes that amplify pain perception in the pain processing pathway. Although there is no ultimate cure for fibromyalgia, some medications can alleviate symptoms of the disease. |
| カテゴリ | 筋骨格疾患 |
| ネットワーク | - |
| 病因遺伝子 | - |
| 病原体 | - |
| 環境要因 | - |
| 発癌物質 | - |
| 治療薬 | 塩酸デュロキセチン [DR:D01179] プレガバリン [DR:D02716] |
| コメント | - |
| リンク | ICD-11: MG30.01 ICD-10: M79.7 MeSH: D005356 |
| 文献 | PMID:26488355 著者 Binkiewicz-Glinska A, Bakula S, Tomczak H, Landowski J, Ruckemann-Dziurdzinska K, Zaborowska-Sapeta K, Kowalski I, Kiebzak W タイトル Fibromyalgia Syndrome - a multidisciplinary approach. 雑誌 Psychiatr Pol 49:801-10 (2015) DOI:10.12740/psychiatriapolska.pl/online-first/4 PMID:26937205 著者 Bhusal S, Diomampo S, Magrey MN タイトル Clinical utility, safety, and efficacy of pregabalin in the treatment of fibromyalgia. 雑誌 Drug Healthc Patient Saf 8:13-23 (2016) DOI:10.2147/DHPS.S95535 |