| D00292 | |
| D number | D00292 |
| Classification | Drug |
| Name | Dexamethasone (JP17/USP/INN); Decadron (TN); Maxidex (TN) |
| Component | - |
| Formula | C22H29FO5 |
| Exact mass | 392.1999 |
| Mol weight | 392.4611 |
| Structural formula |  |
| Sequence | - |
| Sequence type | - |
| Source | - |
| Upper DGroup | Anti-inflammatory DG01955 Corticosteroid DG02068 Glucocorticoid Cyp substrate DG01633 CYP3A substrate Cyp inducer DG01938 CYP2D6 inducer |
| Remark | Same as: C15643 Therapeutic category: 1315 2399 2454 2646 ATC code: A01AC02 C05AA09 D07AB19 D07XB05 D10AA03 H02AB02 R01AD03 S01BA01 S01CB01 S02BA06 S03BA01 Chemical group: DG00011 |
| Activity | - |
| Disease | - |
| Comment | Glucocorticoid, Corticosteroid |
| Target | NR3C1 (GR) [HSA:2908] [KO:K05771] |
| Metabolism | Enzyme: CYP3A4 [HSA:1576], CYP3A5 [HSA:1577], CYP3A7 [HSA:1551] |
| Interaction | CYP induction: CYP2D6 [HSA:1565] |
| Other DBs | CAS: 50-02-2 PubChem: 7847358 ChEBI: 41879 ChEMBL: CHEMBL1698267 CHEMBL1723662 CHEMBL384467 DrugBank: DB01234 PDB-CCD: DEX LigandBox: D00292 NIKKAJI: J1.356K |
| KCF data | - |