| D00437 | |
| D number | D00437 |
| Classification | Drug |
| Name | Nifedipine (JP17/USP/INN); Adalat (TN); Afeditab CR (TN); Procardia (TN) |
| Component | - |
| Formula | C17H18N2O6 |
| Exact mass | 346.1165 |
| Mol weight | 346.3346 |
| Structural formula |  |
| Sequence | - |
| Sequence type | - |
| Source | - |
| Upper DGroup | Cardiovascular agent DG01928 Dihydropyridine calcium channel blocker Other DG01575 Calcium channel blocker DG01496 Calcium channel L type blocker Cyp substrate DG01633 CYP3A substrate |
| Remark | Same as: C07266 Therapeutic category: 2171 ATC code: C08CA05 Vasospastic angina [DS:H01632] Chronic stable angina [DS:H01632] |
| Activity | - |
| Disease | - |
| Comment | Dihydropyridine derivative |
| Target | CACNA1C [HSA:775] [KO:K04850]; CACNA1D [HSA:776] [KO:K04851]; CACNA1F [HSA:778] [KO:K04853]; CACNA1S [HSA:779] [KO:K04857] |
| Metabolism | Enzyme: CYP3A4 [HSA:1576], CYP3A5 [HSA:1577] |
| Interaction | Transporter inhibition: ABCB11 [HSA:8647] |
| Other DBs | CAS: 21829-25-4 PubChem: 7847503 ChEBI: 7565 ChEMBL: CHEMBL193 DrugBank: DB01115 LigandBox: D00437 NIKKAJI: J3.467C |
| KCF data | - |