| D00821 | |
| D number | D00821 |
| Classification | Drug |
| Name | Venlafaxine hydrochloride (JAN/USAN); Effexor (TN) |
| Component | - |
| Formula | C17H27NO2. HCl |
| Exact mass | 313.1809 |
| Mol weight | 313.8627 |
| Structural formula |  |
| Sequence | - |
| Sequence type | - |
| Source | - |
| Upper DGroup | Neuropsychiatric agent DG01658 Serotonin and norepinephrine reuptake inhibitor Cyp substrate DG01644 CYP2D6 substrate Cyp inhibitor DG01645 CYP2D6 inhibitor |
| Remark | Therapeutic category: 1179 ATC code: N06AX16 Chemical group: DG00959 Generalized anxiety disorder [DS:H01662] Social anxiety disorder [DS:H01670] Panic disorder [DS:H01664] |
| Activity | - |
| Disease | - |
| Comment | serotonin norepinephrine reuptake inhibitor (SNRI) |
| Target | SLC6A4 (HTT) [HSA:6532] [KO:K05037]; SLC6A2 (NAT1) [HSA:6530] [KO:K05035] |
| Metabolism | Enzyme: CYP2D6 [HSA:1565] |
| Interaction | Genomic biomarker: CYP2D6 [HSA:1565] CYP inhibition: CYP2D6 [HSA:1565] |
| Other DBs | CAS: 99300-78-4 PubChem: 7847886 ChEBI: 9944 ChEMBL: CHEMBL1201066 DrugBank: DB00285 LigandBox: D00821 NIKKAJI: J397.344A |
| KCF data | - |