| D02086 | |
| D number | D02086 |
| Classification | Drug |
| Name | Lidocaine hydrochloride (JAN/USP); Lidocaine injection (JP17); Dalcaine (TN); Xylocaine (TN) |
| Component | - |
| Formula | C14H22N2O. HCl |
| Exact mass | 270.1499 |
| Mol weight | 270.7982 |
| Structural formula |  |
| Sequence | - |
| Sequence type | - |
| Source | - |
| Upper DGroup | Cardiovascular agent DG01653 Antiarrhythmics DG01652 Class I antiarrhythmic agent DG01651 Class Ib antiarrhythmic agent Neuropsychiatric agent DG02030 Anesthetics DG01675 Local anesthetic DG01673 Amide type local anesthetic DG01675 Local anesthetic DG01673 Amide type local anesthetic Cyp substrate DG01892 CYP1A2 substrate DG01644 CYP2D6 substrate DG01633 CYP3A substrate |
| Remark | Therapeutic category: 1214 2129 ATC code: C01BB01 C05AD01 D04AB01 N01BB02 R02AD02 S01HA07 S02DA01 Chemical group: DG00196 |
| Activity | - |
| Disease | - |
| Comment | Class I antiarrhythmic agent (Ib) Anilide derivative |
| Target | SCN1A [HSA:6323] [KO:K04833]; SCN2A [HSA:6326] [KO:K04834]; SCN3A [HSA:6328] [KO:K04836]; SCN4A [HSA:6329] [KO:K04837]; SCN5A [HSA:6331] [KO:K04838]; SCN8A [HSA:6334] [KO:K04840]; SCN9A [HSA:6335] [KO:K04841]; SCN10A [HSA:6336] [KO:K04842]; SCN11A [HSA:11280] [KO:K04843] |
| Metabolism | Enzyme: CYP1A2 [HSA:1544], CYP3A4 [HSA:1576], CYP2D6 [HSA:1565] Transporter: SLC22A3 [HSA:6581] |
| Interaction | |
| Other DBs | CAS: 73-78-9 PubChem: 7849147 ChEBI: 50512 ChEMBL: CHEMBL541521 DrugBank: DB00281 LigandBox: D02086 NIKKAJI: J231.458D J5.631F |
| KCF data | - |