| D07595 | |
| D number | D07595 |
| Classification | Drug |
| Name | Fosphenytoin sodium hydrate (JAN); Fostoin (TN) |
| Component | - |
| Formula | C16H13N2O6P. 7H2O. 2Na |
| Exact mass | 532.1046 |
| Mol weight | 532.3445 |
| Structural formula |  |
| Sequence | - |
| Sequence type | - |
| Source | - |
| Upper DGroup | Neuropsychiatric agent DG02031 Hydantoin antiepileptics Cyp substrate DG01639 CYP2C19 substrate Cyp inducer DG01635 CYP3A4 inducer |
| Remark | Therapeutic category: 1132 ATC code: N03AB05 Chemical group: DG00847 |
| Activity | - |
| Disease | - |
| Comment | Hydantoin derivative Active form of prodrug: Phenytoin [DR:D00512] |
| Target | SCN1A [HSA:6323] [KO:K04833]; SCN2A [HSA:6326] [KO:K04834]; SCN3A [HSA:6328] [KO:K04836]; SCN4A [HSA:6329] [KO:K04837]; SCN5A [HSA:6331] [KO:K04838]; SCN8A [HSA:6334] [KO:K04840]; SCN9A [HSA:6335] [KO:K04841]; SCN10A [HSA:6336] [KO:K04842]; SCN11A [HSA:11280] [KO:K04843] |
| Metabolism | Enzyme: CYP2C9 [HSA:1559]; CYP2C19 [HSA:1557] |
| Interaction | CYP induction: CYP3A4 [HSA:1576], CYP2B6 [HSA:1555] Transporter induction: ABCB1 [HSA:5243] |
| Other DBs | PubChem: 96024448 LigandBox: D07595 |
| KCF data | - |