D07595 | |
D number | D07595 |
Classification | Drug |
Name | Fosphenytoin sodium hydrate (JAN); Fostoin (TN) |
Component | - |
Formula | C16H13N2O6P. 7H2O. 2Na |
Exact mass | 532.1046 |
Mol weight | 532.3445 |
Structural formula | ![]() |
Sequence | - |
Sequence type | - |
Source | - |
Upper DGroup | Neuropsychiatric agent DG02031 Hydantoin antiepileptics Cyp substrate DG01639 CYP2C19 substrate Cyp inducer DG01635 CYP3A4 inducer |
Remark | Therapeutic category: 1132 ATC code: N03AB05 Chemical group: DG00847 |
Activity | - |
Disease | - |
Comment | Hydantoin derivative Active form of prodrug: Phenytoin [DR:D00512] |
Target | SCN1A [HSA:6323] [KO:K04833]; SCN2A [HSA:6326] [KO:K04834]; SCN3A [HSA:6328] [KO:K04836]; SCN4A [HSA:6329] [KO:K04837]; SCN5A [HSA:6331] [KO:K04838]; SCN8A [HSA:6334] [KO:K04840]; SCN9A [HSA:6335] [KO:K04841]; SCN10A [HSA:6336] [KO:K04842]; SCN11A [HSA:11280] [KO:K04843] |
Metabolism | Enzyme: CYP2C9 [HSA:1559]; CYP2C19 [HSA:1557] |
Interaction | CYP induction: CYP3A4 [HSA:1576], CYP2B6 [HSA:1555] Transporter induction: ABCB1 [HSA:5243] |
Other DBs | PubChem: 96024448 LigandBox: D07595 |
KCF data | - |