| D10120 | |
| D number | D10120 |
| Classification | Drug |
| Name | Esomeprazole strontium (USAN); Esomeprazole strontium tetrahydrate |
| Component | - |
| Formula | (C17H18N3O3S)2. 4H2O. Sr |
| Exact mass | 848.1616 |
| Mol weight | 848.4974 |
| Structural formula |  |
| Sequence | - |
| Sequence type | - |
| Source | - |
| Upper DGroup | Gastrointestinal agent DG01646 Proton pump inhibitor (PPI) DG01975 Agents for peptic ulcer DG01646 Proton pump inhibitor (PPI) Cyp substrate DG01639 CYP2C19 substrate DG01633 CYP3A substrate Cyp inhibitor DG01933 CYP2C19 inhibitor Cyp inducer DG01637 CYP1A2 inducer |
| Remark | ATC code: A02BC05 Chemical group: DG00023 Gastric ulcer [DS:H01634] Duodenal ulcer [DS:H01634] Zollinger-Ellison syndrome [DS:H01522] |
| Activity | - |
| Disease | - |
| Comment | Benzimidazole derivative Treatment of gastric acid disorders |
| Target | ATP4A [HSA:495] [KO:K01542]; ATP4B [HSA:496] [KO:K01543] |
| Metabolism | Enzyme: CYP2C19 [HSA:1557], CYP3A4 [HSA:1576] |
| Interaction | Genomic biomarker: CYP2C19 [HSA:1557] CYP induction: CYP1A2 [HSA:1544] CYP inhibition: CYP2C19 [HSA:1557] |
| Other DBs | CAS: 934714-36-0 PubChem: 135626838 ChEMBL: CHEMBL2146140 LigandBox: D10120 |
| KCF data | - |