| D10466 | |
| D number | D10466 |
| Classification | Drug |
| Name | Vonoprazan fumarate (JAN); Takecab (TN) |
| Component | - |
| Formula | C17H16FN3O2S. C4H4O4 |
| Exact mass | 461.1057 |
| Mol weight | 461.4634 |
| Structural formula |  |
| Sequence | - |
| Sequence type | - |
| Source | - |
| Upper DGroup | Cyp inhibitor DG01933 CYP2C19 inhibitor DG01915 CYP3A5 inhibitor |
| Remark | Therapeutic category: 2329 |
| Activity | - |
| Disease | - |
| Comment | Potassium competitive acid blocker (P-CAB) |
| Target | ATP4A [HSA:495] [KO:K01542]; ATP4B [HSA:496] [KO:K01543] |
| Metabolism | Enzyme: CYP3A4 [HSA:1576], CYP2B6 [HSA:1555], CYP2C19 [HSA:1557], CYP2D6 [HSA:1565], SULT2A1 [HSA:6822] |
| Interaction | CYP induction: CYP1A2 [HSA:1544] CYP inhibition: CYP2B6 [HSA:1555], CYP2C19 [HSA:1557], CYP3A4 [HSA:1576], CYP3A5 [HSA:1577] |
| Other DBs | CAS: 881681-01-2 PubChem: 172232559 ChEMBL: CHEMBL2064032 |
| KCF data | - |