Life science projects in Japan
Former name: Genome, post genome projects in Japan
| Functional RNA project | |
| Project Name | Functional RNA project |
| Start Year | 2005 |
| End Year | 2009 |
| Implementing Period | 2005-2009 |
| Budget Amount | 2.235 billion yen (2005-2007) |
| Major Researchers | Chief Researcher: Kimitsuna Watanabe (Advanced Industrial Science and Technology - Biological Information Research Center) Companies (13), Independent administrative institutions (2) and university laboratories (17). - Bioinformatics: Advanced Industrial Science and Technology, University of Tokyo (Asai), Keio University (Sakakibara, Kanai) - Development of tools - Functional analysis |
| Summary | Functional analysis of functional RNAs |
| Major Features of Project | Following projects are carried out. 1. Development of bioinformatics technologies to identify and analyze functional ncRNAs. 2. Development of supporting technologies and tools for functional ncRNA analysis. 3. Function analysis of ncRNAs. |
| Description of Project | Excerpts from "Functional RNA Project Introduction Page" (JBIC) (http://www.jbic.or.jp/bio/english/activity/f_rna_pj/index_rn.html ): Recent studies have revealed that higher organisms have many RNAs that do not encode proteins and that these non-coding RNAs (ncRNAs) play important roles in development and differentiation processes as well as in disease processes. In vivo function of these ncRNAs will be investigated, and the results will be applied to diagnosis and treatment of various diseases and realization of regenerative medicine. Explanation of Project Overview(Japanese) FY2006 Implementation Policies(Japanese) FY2007 Implementation Policies(Japanese) |
| Public Release Status | Only the data related to technology development that predict and identify functional RNAs are publicly released. |
| Classification of Database Public Release Status | Partially publicly released |
| Public Database | - fRNAdb (Secondary database of functional information and literature information) ( http://www.ncrna.org/frnadb ) - UCSC GenomeBrowser for Functional RNA (Functional RNA is displayed on the UCSC GenomeBrowser.) ( http://www.ncrna.org/glocal ) |
| Data Download Site | - |
| Website | - Project Introduction Page (JBIC) ( http://www.jbic.or.jp/bio/english/activity/f_rna_pj/index_rn.html ) - The portal site for the Funtional RNA Project ( http://www.ncrna.org/ ) |
| Implementing Ministry/Agency | Ministry of Economy, Trade and Industry (METI) |
| Commercialization Re | NA |
| Reports | 1. JBIC FY2006 Activity Plan ( http://www.mext.go.jp/b_menu/koueki/shinkou/07/11/010.pdf , Japanese) 2. JBIC FY2006 Activity Report ( http://www.jbic.or.jp/bio/g/fil_actv/h18reprt.pdf ,Japanese) 3. JBIC FY2007 Activity Plan ( http://www.jbic.or.jp/bio/g/files/07/h19act_p.pdf ,Japanese) |
| Evaluation Reports | - |
| Other Literatures | - New Trends in Life Science: Functional RNA Project (1) ( http://www.worldtimes.co.jp/special2/rna/050824.html , Japanese) - Functional RNA Project (Extraction and functional analysis of sense and antisense genes in human and mouse) ( http://www.kri.sfc.keio.ac.jp/kris-yp/cgi/view_page.cgi?research_id=136 , Japanese) - fRNAdb: a platform for mining/annotating functional RNA candidates from non-coding RNA sequences, Nucleic Acids Research 2007 35(Database issue):D145-D148 ( http://nar.oxfordjournals.org/cgi/content/full/35/suppl_1/D145 ) |