Life science projects in Japan

Former name: Genome, post genome projects in Japan


Research for the Future Program (Genome Research)
Project Name Research for the Future Program (Genome Research)
Start Year 1996
End Year 2004
Implementing Period 1996-1999 (completed) , Human Genome 2000-2004 (completed) Genome Research
Budget Amount 11.08 billion yen (2000-2004)
Major Researchers Research Promotion Committee Chairpersons: Kenichi Matsubara (DNA Chip Research Inc.) and Hiroshi Yoshikawa (Adviser, JT Biohistory Research Hall)
Project Leaders:
- Itsuro Inoue (University of Tokyo, Institute of Medical Science)
- Yusuke Nakamura (University of Tokyo, The Institute of Medical Science)
- Satoru Miyano (University of Tokyo, Institute of Medical Science)
- Shoji Tsuji (University of Tokyo Graduate School of Medicine)
- Mitsuo Itakura (University of Tokushima, Institute for Genome Research)
- Nobuyoshi Shimizu (Keio University School of Medicine)
- Hidetoshi Inoko (Tokai University School of medicine)
- Mitsuru Emi (Institute of Gerontology, Nippon Medical School)
- Minoru Kanehisa (Kyoto University, Institute for Chemical Research)
- Naoyuki Kamatani (Institute of Rheumatology, Tokyo Women's Medical University)
- Hideo Hayashi (University of Tsukuba, Institute of Basic Medical Sciences)
- Satoru Kuhara (Kyushu University, Faculty of Agriculture)
- Masatoshi Takeda (Osaka University Graduate School of Medicine)
Summary Human genome sequencing and its applied studies
Major Features of Project From the List of Research Themes for Research for the Future Program (Genome Research), ( http://www.jsps.go.jp/j-rftf/project/l014.htm , Japanese)
* Itsuro Inoue (University of Tokyo, Institute of Medical Science) Systematic Genetic Study of Asthma and Atopic Dermatitis Based on the Genome-Wide SNP Informatics
* Yusuke Nakamura (University of Tokyo, The Institute of Medical Science) Systematic Expression Profile Analysis and its Application to Personalized Medicine
* Satoru Miyano (University of Tokyo, Institute of Medical Science) Genome-Wide Analysis of Genes Related to Disease Susceptibility and Drug Responsiveness
* Shoji Tsuji (University of Tokyo) Identification of Genes Involved in Brain Diseases
* Mitsuo Itakura (University of Tokushima) Whole Body Functional Genomics Directing toward the Understanding of Disease-Related Genes
* Nobuyoshi Shimizu (Keio University) Human Molecular Biology and Medicine Based on Genome Analysis
* Hidetoshi Inoko (Tokai University) Identification of Disease-Related Genes Using Microsatellite Polymorphisms
* Mitsuru Emi (Nippon Medical School) Genetic Analysis of Osteoporosis by Systematic SNP Typing
* Minoru Kanehisa (Kyoto University) Biological Systems Database and Genome Information Science
* Naoyuki Kamatani (Tokyo Women's Medical University) Development and Application of Computer Programs for Mapping Disease-Related Genes Using Polymorphic Markers
* Tetsuya Hayashi (University of Miyazaki) Virulent/Valuable Genome System in Microorganism
* Satoru Kuhara (Kyushu University) Computational Biology on Genome Function Based on Expression and Phenotype Data
* Masatoshi Takeda (Osaka University) Analysis of Alzheimer Disease-Related Genes
Description of Project Excerpts from Overview of Research for the Future Program (Genome Research)(
http://www.jsps.go.jp/j-rftf/outl/l014.htm, Japanese)
In this Project, new genomic analysis techniques will be developed, and will be utilized to help using genomic data and genomic polymorphism data for successful identification of disease genes. Moreover, new findings to be gained from the results of studies of model organisms and disease models will be applied to these data to develop new therapeutic approaches against malignant diseases, hypertension, diabetes, asthma and atopic disease and to delay the onset of these diseases,
Also, bioinformatics research will be carried out to understand the systems of life from the genomic information.
Furthermore, experimental and bioinformatic analyses of the genome of microorganisms and model organisms will be performed to discover pathogenic and useful genes related to human disease and health, and to elucidate gene functions, and finally technological and theoretical models that are necessary for human genome functional analyses will be established through the evolutionary studies of the systems of life.
Public Release Status NA
Classification of Database Public Release Status Partially shared,Partially publicly released,Partially unknown
Public Database Leader Names (Public database)
- Inoue
- Nakamura (JSNP( http://snp.ims.u-tokyo.ac.jp/index.html ))
- Tsuji
- Miyano
- Itakura (Asian SNPs( http://www.genome.tokushima-u.ac.jp/dgi/ENGDGI/ASNPs_E/index_English.html ))
- Shimizu (KMDB/MutationView( http://mutview.dmb.med.keio.ac.jp/ ))
- Inoko
- Emi
- Kanehisa (KEGG( http://www.kegg.jp/ ))
- Kamatani ( http://www.jpma.or.jp/psc/11data/index.html , found in the Summary of Report of Research Project Results)
- Hayashi
- Kuhara
- Takeda
Data Download Site -
Website Research for the Future Program( http://www.jsps.go.jp/j-rftf/project/l014.htm )
Implementing Ministry/Agency Ministry of Education, Culture, Sports, Science and Technology (MEXT)
Reports List of Reports of Research Project Results for FY2004 Research for the Future Program( http://www.jsps.go.jp/j-rftf/saishu/h16/index.html , Japanese)
Evaluation Reports - Final evaluation ( http://www.jsps.go.jp/j-rftf/life_i.htm , Japanese )(Click the frame on left "Final Evaluation/Researches that started in FY2000.")
- Summary of "Final Evaluation" Report( http://www.jsps.go.jp/j-rftf/saishu_hyouka_12/data/houkoku_h12.pdf , Japanese )
- Summary of Research Project Results( http://www.jsps.go.jp/j-rftf/life_i.htm , Japanese)(Click "Summary of Research Project Results" on the page for final evaluation.)
Other Literatures -