Medals oligonucleic drug ID monrd0027
ATC Classification -
Product Name Mongersen
Synonims GED-0301
Country US
Company Celgene Corporation
phase III
Type Antisense
Adaptation Diseases Crohn’s disease
Target Molecule SMAD7
Remarks Mongersen is a drug under development treating inflammation associated with Crohn's disease.
As a result of double-blind, placebo-controlled phase II study on patients with Crohn's disease, the remission rate and clinical response were significantly higher compared to the placebo control group.
A phase III study has been carried out.
Nucleic Acid Sequence -
DrugBank -
TargetProtein - UniProt O15105
TargetProtein - PDB 2LTW