| H00343 | |
| H number | H00343 |
| Name | Diphtheria |
| Description | Diphtheria is a contagious and potentially life-threatening childhood disease caused by Corynebacterium diphtheriae. In industrialized countries, immunization against diphtheria became widespread in the 1940s and the incidence of the disease markedly decreased. However, diphtheria still remains endemic in several regions including Africa, India, Bangladesh, Vietnam, the tropics, and South America. Moreover, a large proportion of adults in industrialized countries are now susceptible to diphtheria because the protection by vaccine does not last for long time unless periodic booster is given. |
| Category | Bacterial infectious disease |
| Network | - |
| Gene | - |
| Pathogen | Corynebacterium diphtheriae [GN:cdi cdp cdz cdd cdw cdv] diphtheria toxin [KO:K00776] |
| Env factor | - |
| Carcinogen | - |
| Drug | Erythromycin [DR:D00140] Erythromycin ethylsuccinate [DR:D01361] Erythromycin lactobionate [DR:D02009] Erythromycin stearate [DR:D02184] Penicillin G potassium [DR:D01053] Penicillin G procaine [DR:D02461] Penicillin G sodium [DR:D05408] Freeze-dried diphtheria antitoxin, equine [DR:D03925] |
| Comment | - |
| Other DBs | ICD-11: 1C17 ICD-10: A36 MeSH: D004165 MedlinePlus: 001608 |
| Reference | PMID:15049077 AUTHORS Mattos-Guaraldi AL, Moreira LO, Damasco PV, Hirata Junior R TITLE Diphtheria remains a threat to health in the developing world--an overview. JOURNAL Mem Inst Oswaldo Cruz 98:987-93 (2003) DOI:10.1590/S0074-02762003000800001 PMID:7489768 AUTHORS Galazka AM, Robertson SE TITLE Diphtheria: changing patterns in the developing world and the industrialized world. JOURNAL Eur J Epidemiol 11:107-17 (1995) DOI:10.1007/BF01719955 PMID:7489783 AUTHORS Galazka AM, Robertson SE, Oblapenko GP TITLE Resurgence of diphtheria. JOURNAL Eur J Epidemiol 11:95-105 (1995) DOI:10.1007/BF01719954 |