| H00367 | |
| H number | H00367 |
| Name | Infectious mononucleosis; Epstein-Barr virus (EBV) infection |
| Description | Epstein-Barr virus (EBV) is a common gammaherpesvirus whose initial infection manifests as infectious mononucleosis that is defined as a clinical triad of fever, pharyngitis, and adenopathy. EBV establishes a life-long asymptomatic infection in B cells and can contribute to oncogenesis including Burkitt's lymphoma, nasopharyngeal carcinoma, Hodgkin lymphoma, and post-transplant B cell lymphomas. |
| Category | Viral infectious disease DIS_PATHWAY hsa05169 Epstein-Barr virus infection |
| Network | nt06165 Epstein-Barr virus (EBV) |
| Gene | - |
| Pathogen | Human herpesvirus 4 (Epstein-Barr virus) [GN:T40079] |
| Env factor | - |
| Carcinogen | - |
| Drug | - |
| Comment | - |
| Other DBs | ICD-11: 1D81 ICD-10: B27.0 MeSH: D020031 D002051 D007244 MedlinePlus: 000591 |
| Reference | PMID:8380053 AUTHORS Straus SE, Cohen JI, Tosato G, Meier J TITLE NIH conference. Epstein-Barr virus infections: biology, pathogenesis, and management. JOURNAL Ann Intern Med 118:45-58 (1993) DOI:10.7326/0003-4819-118-1-199301010-00009 |