| H00377 | |
| H number | H00377 |
| Name | Rabies |
| Description | Rabies is a typical zoonotic disease caused by rabies virus that belongs to the genus Lyssavirus, within the family Rhabdoviridae and the order Mononegavirales of -ssRNA viruses. Dogs are the major vectors. Rabies affects the central nervous system and causes fatal encephalomyelitis. |
| Category | Viral infectious disease |
| Network | - |
| Gene | - |
| Pathogen | Rabies virus (RABV) [GN:T40022] |
| Env factor | - |
| Carcinogen | - |
| Drug | Rabies vaccine [DR:D06504] |
| Comment | Preexposure vaccination with modern cell culture vaccine is recommended for people at high risk of exposure. Postexposure prophylaxis consists of wound cleansing and immunization with modern cell culture vaccine, together with administration of rabies immune globulin. There is no certain cure for rabies except supportive care. |
| Other DBs | ICD-11: 1C82 ICD-10: A82 MeSH: D011818 MedlinePlus: 001334 |
| Reference | PMID:22348291 AUTHORS Yousaf MZ, Qasim M, Zia S, Khan Mu, Ashfaq UA, Khan S TITLE Rabies molecular virology, diagnosis, prevention and treatment. JOURNAL Virol J 9:50 (2012) DOI:10.1186/1743-422X-9-50 PMID:18297443 AUTHORS Takayama N TITLE Rabies: a preventable but incurable disease. JOURNAL J Infect Chemother 14:8-14 (2008) DOI:10.1007/s10156-007-0573-0 PMID:18165217 AUTHORS Leung AK, Davies HD, Hon KL TITLE Rabies: epidemiology, pathogenesis, and prophylaxis. JOURNAL Adv Ther 24:1340-7 (2007) DOI:10.1007/BF02877781 |