| H00427 | |
| H number | H00427 |
| Name | Relapsing fever |
| Description | Relapsing fever is a bacterial infectious disease caused by spirochaetes belonging to the genus Borrelia and is transmitted by ticks or lice. Louse-borne relapsing fever is now geographically limited, but tick-borne relapsing fever still causes major health problems in Africa. The symptoms are variable. Although relapsing fever is considered a transient disease, it persists as a residual infection in the brain, which can be reactivated on immunosuppression. |
| Category | Bacterial infectious disease |
| Network | - |
| Gene | - |
| Pathogen | Borrelia recurrentis [GN:bre] (Louse-borne relapsing fever) Borrelia duttonii [GN:bdu] (Tick-borne relapsing fever) Borrelia hermsii [GN:bhr bhi] (Tick-borne relapsing fever) Borrelia turicatae [GN:btu] (Tick-borne relapsing fever) Borrelia crocidurae [GN:bcw] (Tick-borne relapsing fever) Borrelia coriaceae [GN:bcoi] (Tick-borne relapsing fever) Borrelia miyamotoi [GN:bmo] (Tick-borne relapsing fever) Candidatus Borrelia fainii [GN: bfai] (Tick-borne relapsing fever) |
| Env factor | - |
| Carcinogen | - |
| Drug | Tetracycline hydrochloride [DR:D02122] Doxycycline [DR:D00307] Doxycycline hyclate [DR:D02129] Doxycycline calcium [DR:D03903] Minocycline hydrochloride [DR:D00850] Demeclocycline hydrochloride [DR:D00290] |
| Comment | Vectors: Pediculus humanus (body louse), Ornithodoros moubata (African tick) |
| Other DBs | ICD-11: 1C1J ICD-10: A68 MeSH: D012061 MedlinePlus: 001350 |
| Reference | PMID:19886891 AUTHORS Cutler SJ TITLE Relapsing fever--a forgotten disease revealed. JOURNAL J Appl Microbiol 108:1115-22 (2010) DOI:10.1111/j.1365-2672.2009.04598.x PMID:19623064 AUTHORS Larsson C, Andersson M, Bergstrom S TITLE Current issues in relapsing fever. JOURNAL Curr Opin Infect Dis 22:443-9 (2009) DOI:10.1097/QCO.0b013e32832fb22b PMID:16704771 AUTHORS Cutler SJ TITLE Possibilities for relapsing fever reemergence. JOURNAL Emerg Infect Dis 12:369-74 (2006) DOI:10.3201/eid1205.050899 |