H00795 | |
H number | H00795 |
Name | Seborrhea-like dermatitis with psoriasiform element |
Description | Seborrhea-like dermatosis with psoriasiform elements is a chronic dermatosis characterized by common dandruffs and eczematous or psoriasiform plaques. Enhanced keratinocyte proliferation and dermal infiltration of inflammatory cells are observed in the disease. Mutations in ZNF750, which encodes a putative C2H2 zinc finger protein, have been reported. |
Category | Immune system disease; Skin disease |
Network | - |
Gene | ZNF750 [HSA:79755] [KO:K24377] |
Pathogen | - |
Env factor | - |
Carcinogen | - |
Drug | - |
Comment | - |
Other DBs | ICD-11: EA81 MeSH: C565217 OMIM: 610227 |
Reference | PMID:16751772 AUTHORS Birnbaum RY, Zvulunov A, Hallel-Halevy D, Cagnano E, Finer G, Ofir R, Geiger D, Silberstein E, Feferman Y, Birk OS TITLE Seborrhea-like dermatitis with psoriasiform elements caused by a mutation in ZNF750, encoding a putative C2H2 zinc finger protein. JOURNAL Nat Genet 38:749-51 (2006) DOI:10.1038/ng1813 |