| H00975 | |
| H number | H00975 |
| Name | Rotaviral enteritis; Rotaviral gastroenteritis |
| Description | Rotaviral enteritis is the main diarrheal disease in infants caused by rotavirus infection. Rotaviruses are members of the Reoviridae family and contain genomes consisting of eleven segments of double-stranded RNA. Rotavirus is transmitted primarily via the fecal-oral route. |
| Category | Viral infectious disease |
| Network | - |
| Gene | - |
| Pathogen | Rotavirus A [GN:T40092] Human rotavirus B [GN:T40123] Rotavirus C [GN:T40094] NSP4 enterotoxin [VG:7011361] |
| Env factor | - |
| Carcinogen | - |
| Drug | Live attenuated human rota virus vaccine, oral [DR:D10193] Rotavirus vaccine, live, oral, pentavalent [DR:D10211] |
| Comment | - |
| Other DBs | ICD-11: 1A22 ICD-10: A08.0 MeSH: D012400 |
| Reference | PMID:2855916 AUTHORS Leung AK, Pai CH TITLE Rotavirus gastroenteritis. JOURNAL J Diarrhoeal Dis Res 6:188-207 (1988) PMID:22687427 AUTHORS Ogden KM, Johne R, Patton JT TITLE Rotavirus RNA polymerases resolve into two phylogenetically distinct classes that differ in their mechanism of template recognition. JOURNAL Virology 431:50-7 (2012) DOI:10.1016/j.virol.2012.05.011 PMID:29119972 AUTHORS Crawford SE, Ramani S, Tate JE, Parashar UD, Svensson L, Hagbom M, Franco MA, Greenberg HB, O'Ryan M, Kang G, Desselberger U, Estes MK TITLE Rotavirus infection. JOURNAL Nat Rev Dis Primers 3:17083 (2017) DOI:10.1038/nrdp.2017.83 |