| H01165 | |
| H number | H01165 |
| Name | Novosphingobium aromaticivorans infection |
| Description | Novosphingobium aromaticivorans is a gram-negative aerobic bacterium that is well known for its ability to degrade phenolic structures. N. aromaticivorans has been reported to trigger the development of primary biliary cirrhosis because it expresses proteins that have high homology with human pyruvate dehydrogenase component (PDC-E2), which can act as an immunological trigger for T cell-mediated tissue destruction. |
| Category | Bacterial infectious disease |
| Network | - |
| Gene | - |
| Pathogen | Novosphingobium aromaticivorans PDC-E2 like protein |
| Env factor | - |
| Carcinogen | - |
| Drug | - |
| Comment | - |
| Other DBs | - |
| Reference | PMID:15554995 AUTHORS Kaplan MM TITLE Novosphingobium aromaticivorans: a potential initiator of primary biliary cirrhosis. JOURNAL Am J Gastroenterol 99:2147-9 (2004) DOI:10.1111/j.1572-0241.2004.41121.x |