| H01409 | |
| H number | H01409 |
| Name | Methicillin-sensitive Staphylococcus aureus (MSSA) infection |
| Description | Staphylococcus aureus is a Gram-positive human commensal bacterium persistently colonizing the anterior nares of about 30% of the human population. Methicillin-resistant S. aureus (MRSA) is known to have evolved from methicillin-susceptible S. aureus (MSSA) after acquiring the staphylococcal cassette chromosome mec (SCCmec) element which includes the mecA gene coding for resistance to the antibiotic methicillin. A highly cytotoxic and clinically virulent methicillin-sensitive strain, S. aureus strain 6850 is a well-characterized prototype strain isolated from a patient with a skin abscess which had progressed to S. aureus bacteremia, osteomyelitis, septic arthritis, and multiple systemic abscesses. |
| Category | Bacterial infectious disease DIS_PATHWAY hsa05150 Staphylococcus aureus infection |
| Network | - |
| Gene | - |
| Pathogen | Staphylococcus aureus [GN:sas suc sud saue] |
| Env factor | - |
| Carcinogen | - |
| Drug | Quinupristin and dalfopristin [DR:D00854] |
| Comment | - |
| Other DBs | ICD-10: B95 MeSH: D013203 |
| Reference | PMID:24072870 AUTHORS Fraunholz M, Bernhardt J, Schuldes J, Daniel R, Hecker M, Sinha B TITLE Complete Genome Sequence of Staphylococcus aureus 6850, a Highly Cytotoxic and Clinically Virulent Methicillin-Sensitive Strain with Distant Relatedness to Prototype Strains. JOURNAL Genome Announc 1:e00775-13 (2013) DOI:10.1128/genomeA.00775-13 PMID:23183202 AUTHORS Lim KT, Yeo CC, Suhaili Z, Thong KL TITLE Comparison of methicillin-resistant and methicillin-sensitive Staphylococcus aureus strains isolated from a tertiary hospital in Terengganu, Malaysia. JOURNAL Jpn J Infect Dis 65:502-9 (2012) DOI:10.7883/yoken.65.502 |