H01445 | |
H number | H01445 |
Name | Acne vulgaris |
Description | Acne is a chronic inflammatory disease of the pilosebaceous unit resulting from androgen-induced increased sebum production, altered keratinization, inflammation, and bacterial colonization of hair follicles on the face, neck, chest, and back by Propionibacterium acnes. P. acnes is a Gram-positive bacterium that forms part of the normal flora of the skin, oral cavity, large intestine, the conjunctiva and the external ear canal. Although P. acnes is primarily recognized for its role in acne, it's also famous as an opportunistic pathogen causing a range of postoperative and device-related infections. |
Category | Bacterial infectious disease |
Network | - |
Gene | - |
Pathogen | Propionibacterium acnes [GN:pac pach] |
Env factor | - |
Carcinogen | - |
Drug | Tetracycline hydrochloride [DR:D02122] Doxycycline [DR:D00307] Doxycycline calcium [DR:D03903] Minocycline hydrochloride [DR:D00850] Tazarotene [DR:D01132] Tretinoin [DR:D00094] Adapalene [DR:D01112] Trifarotene [DR:D11225] Clindamycin phosphate and tretinoin [DR:D11084] Adapalene and benzoyl peroxide [DR:D10792] Benzoyl peroxide [DR:D03093] Clindamycin phosphate and benzoyl peroxide [DR:D10602] Benzoyl peroxide and erythromycin [DR:D11646] Benzoyl peroxide and tretinoin [DR:D12338] Clindamycin phosphate [DR:D01073] Erythromycin [DR:D00140] Sulfacetamide sodium [DR:D00871] Dapsone [DR:D00592] Clascoterone [DR:D11451] Norgestimate and ethinyl estradiol [DR:D10590] Sarecycline hydrochloride [DR:D10667] |
Comment | - |
Other DBs | ICD-11: ED80 ICD-10: L70.0 MeSH: D000152 MedlinePlus: 000873 |
Reference | PMID:21880356 AUTHORS Williams HC, Dellavalle RP, Garner S TITLE Acne vulgaris. JOURNAL Lancet 379:361-72 (2012) DOI:10.1016/S0140-6736(11)60321-8 PMID:22114965 AUTHORS Perry A, Lambert P TITLE Propionibacterium acnes: infection beyond the skin. JOURNAL Expert Rev Anti Infect Ther 9:1149-56 (2011) DOI:10.1586/eri.11.137 |