| H01447 | |
| H number | H01447 |
| Name | Body dysmorphic disorder |
| Description | Body dysmorphic disorder (BDD) is a psychiatric disorder in which individuals are preoccupied with imagined defects in their appearance, which are not noticeable or appear slight to others. It is characterized by time-consuming behaviors such as mirror gazing, comparing one's appearance with the appearance of others, excessive camouflaging to hide the defect, and seeking reassurance. Patients experience significant distress, disability, and functional impairment, often accompanied by depression and suicidality. There is some clinical and pathologic overlap between obsessive-compulsive disorder (OCD) and BDD such as obsessive thoughts and the performance of ritual behavior. Patients with BDD respond to treatment with serotonergic agents such as clomipramine or selective serotonin reuptake inhibitors (SSRIs), which suggests a dysfunction of central serotonergic neurotransmission as a possible etiological factor. A recent study suggests that cognitive-behavior therapy (CBT) was more effective than treatment with medications. |
| Category | Mental and behavioural disorder |
| Network | - |
| Gene | - |
| Pathogen | - |
| Env factor | - |
| Carcinogen | - |
| Drug | - |
| Comment | In the fifth edition of Diagnostic and Statistical Manual of Mental Disorders (DSM-5), body dysmorphic disorder (BDD) has been subsumed into the obsessive-compulsive disorders and related disorders (OCDRD) category. |
| Other DBs | ICD-11: 6B21 ICD-10: F45.2 MeSH: D057215 |
| Reference | PMID:26345330 AUTHORS Frias A, Palma C, Farriols N, Gonzalez L TITLE Comorbidity between obsessive-compulsive disorder and body dysmorphic disorder: prevalence, explanatory theories, and clinical characterization. JOURNAL Neuropsychiatr Dis Treat 11:2233-44 (2015) DOI:10.2147/NDT.S67636 PMID:18224271 AUTHORS Pavan C, Simonato P, Marini M, Mazzoleni F, Pavan L, Vindigni V TITLE Psychopathologic aspects of body dysmorphic disorder: a literature review. JOURNAL Aesthetic Plast Surg 32:473-84 (2008) DOI:10.1007/s00266-008-9113-2 PMID:25419211 AUTHORS Li W, Arienzo D, Feusner JD TITLE Body Dysmorphic Disorder: Neurobiological Features and an Updated Model. JOURNAL Z Klin Psychol Psychother (Gott) 42:184-191 (2013) DOI:10.1026/1616-3443/a000213 PMID:11926939 (Drug) AUTHORS Phillips KA, Albertini RS, Rasmussen SA TITLE A randomized placebo-controlled trial of fluoxetine in body dysmorphic disorder. JOURNAL Arch Gen Psychiatry 59:381-8 (2002) DOI:10.1001/archpsyc.59.4.381 PMID:23459093 AUTHORS Hofmann SG, Asnaani A, Vonk IJ, Sawyer AT, Fang A TITLE The Efficacy of Cognitive Behavioral Therapy: A Review of Meta-analyses. JOURNAL Cognit Ther Res 36:427-440 (2012) DOI:10.1007/s10608-012-9476-1 |