| H01451 | |
| H number | H01451 |
| Name | Actinomycetoma |
| Description | Mycetoma is an infectious disease of skin and subcutaneous tissue. It can be caused by either bacteria (actinomycetoma) or fungi (eumycetoma [DS:H02385] ). It is endemic in tropical and subtropical regions, predominating between latitudes 15 degrees south and 30 degrees north, called mycetoma belt. Actinomycetoma is most commonly found in Latin America. Although Nocardia brasiliensis, Actinomadura madurae, Actinomadura pelletieri and Streptomyces somaliensis are the common causative organisms of actinomycetoma, the distribution of them shows strong geographic variation. The primary niche of these microorganisms is suggested to be the soil. The infection is thought to start subcutaneously after traumatic inoculation of these microorganisms. |
| Category | Bacterial infectious disease |
| Network | - |
| Gene | - |
| Pathogen | Nocardia brasiliensis [GN:nbr] Nocardiopsis dassonvillei [GN:nda] Actinomadura madurae [GN:amaz] Actinomadura pelletieri Streptomyces somaliensis |
| Env factor | - |
| Carcinogen | - |
| Drug | - |
| Comment | See also H02385 Eumycetoma and H00345 Nocardiosis. |
| Other DBs | ICD-11: 1C43 ICD-10: B47.1 MeSH: D008271 |
| Reference | PMID:11018454 AUTHORS Salinas-Carmona MC TITLE Nocardia brasiliensis: from microbe to human and experimental infections. JOURNAL Microbes Infect 2:1373-81 (2000) DOI:10.1016/S1286-4579(00)01291-0 PMID:26738840 AUTHORS Zijlstra EE, van de Sande WWJ, Welsh O, Mahgoub ES, Goodfellow M, Fahal AH TITLE Mycetoma: a unique neglected tropical disease. JOURNAL Lancet Infect Dis 16:100-112 (2016) DOI:10.1016/S1473-3099(15)00359-X |