| H01469 | |
| H number | H01469 |
| Name | Short bowel syndrome |
| Description | Short bowel syndrome (SBS), also called short gut syndrome or simply short gut, is a malabsorption disorder. It typically occurs in people who lost at least half of their small intestine due to surgical resection for various disorders, including Crohn's disease, volvulus, cancer, or significant damage (injury, trauma). In infants, necrotizing enterocolitis is the most common cause for surgical resection of the small intestines. Patients usually experience symptoms that include abdominal pain, diarrhea. The main treatment is nutritional support such as oral rehydration, parenteral nutrition, enteral nutrition, vitamin and mineral supplements, and special diet. Currently, a recombinant analog of human glucagon-like peptide-2 (GLP-2) teduglutide associated with the treatment for SBS has been reported to improve intestinal absorption. |
| Category | Digestive system disease |
| Network | - |
| Gene | - |
| Pathogen | - |
| Env factor | - |
| Carcinogen | - |
| Drug | Teduglutide [DR:D06053] |
| Comment | - |
| Other DBs | ICD-11: KB89.1 ICD-10: K91.8 MeSH: D012778 |
| Reference | PMID:24486858 AUTHORS Jeppesen PB TITLE Spectrum of short bowel syndrome in adults: intestinal insufficiency to intestinal failure. JOURNAL JPEN J Parenter Enteral Nutr 38:8S-13S (2014) DOI:10.1177/0148607114520994 PMID:23830324 AUTHORS Wall EA TITLE An overview of short bowel syndrome management: adherence, adaptation, and practical recommendations. JOURNAL J Acad Nutr Diet 113:1200-8 (2013) DOI:10.1016/j.jand.2013.05.001 |