H01527 | |
H number | H01527 |
Name | Chronic inflammatory demyelinating polyradiculoneuropathy |
Description | Chronic inflammatory demyelinating polyradiculoneuropathy (CIDP) is a polyneuropathy that is often disabling, with more than 50% of patients reported as having temporary disability, and about 10% eventually becoming persistently disabled. The core clinical features are a chronic progressive or relapsing and remitting, symmetrical, and sensory and motor polyradiculoneuropathy causing weakness of proximal and distal muscles. The etiology is suspected to be of autoimmune origin, and the diagnosis is typically based on clinical history, neurologic examination, electrophysiologic studies, cerebrospinal fluid (CSF) studies, and pathologic examination. CIDP often responds to immune therapies including corticosteroids, plasma exchange, and high-dose intravenous immunoglobulin (IVIg). |
Category | Immune system disease; Nervous system disease |
Network | - |
Gene | - |
Pathogen | - |
Env factor | - |
Carcinogen | - |
Drug | - |
Comment | - |
Other DBs | ICD-11: 8C01.3 ICD-10: G61.8 MeSH: D020277 |
Reference | PMID:26437234 AUTHORS Press R, Hiew FL, Rajabally YA TITLE Steroids for chronic inflammatory demyelinating polyradiculoneuropathy: evidence base and clinical practice. JOURNAL Acta Neurol Scand 133:228-38 (2016) DOI:10.1111/ane.12519 PMID:26203970 AUTHORS Nobile-Orazio E, Gallia F TITLE Update on the treatment of chronic inflammatory demyelinating polyradiculoneuropathy. JOURNAL Curr Opin Neurol 28:480-5 (2015) DOI:10.1097/WCO.0000000000000232 PMID:26008811 AUTHORS Kleyman I, Brannagan TH 3rd TITLE Treatment of chronic inflammatory demyelinating polyneuropathy. JOURNAL Curr Neurol Neurosci Rep 15:47 (2015) DOI:10.1007/s11910-015-0563-z PMID:16519780 AUTHORS Hughes RA, Allen D, Makowska A, Gregson NA TITLE Pathogenesis of chronic inflammatory demyelinating polyradiculoneuropathy. JOURNAL J Peripher Nerv Syst 11:30-46 (2006) DOI:10.1111/j.1085-9489.2006.00061.x |