| H01043 | |
| H番号 | H01043 |
| 名称 | オンコセルカ症 |
| 概要 | Human onchocerciasis is an infection caused by the filarial nematode Onchocerca volvulus transmitted by Simulium blackflies. The disease is endemic in sub-Saharan African countries, the Arabian peninsula, and small parts of Latin America. Persons with onchocerciasis may develop skin diseases such as pruritus, lichenification, and depigmentation, as well as ocular manifestations. Onchocerca volvulus contain Wolbachia bacteria as mutualistic symbionts, and these Wolbachia affects the nematode survival. |
| カテゴリ | 寄生虫感染症 |
| ネットワーク | - |
| 病因遺伝子 | - |
| 病原体 | Onchocerca volvulus |
| 環境要因 | - |
| 発癌物質 | - |
| 治療薬 | - |
| コメント | Vector: Simulium blackflies |
| リンク | ICD-11: 1F6A ICD-10: B73 MeSH: D009855 |
| 文献 | PMID:20739055 著者 Taylor MJ, Hoerauf A, Bockarie M タイトル Lymphatic filariasis and onchocerciasis. 雑誌 Lancet 376:1175-85 (2010) DOI:10.1016/S0140-6736(10)60586-7 PMID:20801094 著者 Cupp EW, Sauerbrey M, Richards F タイトル Elimination of human onchocerciasis: history of progress and current feasibility using ivermectin (Mectizan((R))) monotherapy. 雑誌 Acta Trop 120 Suppl 1:S100-8 (2011) DOI:10.1016/j.actatropica.2010.08.009 PMID:21734243 著者 Tamarozzi F, Halliday A, Gentil K, Hoerauf A, Pearlman E, Taylor MJ タイトル Onchocerciasis: the role of Wolbachia bacterial endosymbionts in parasite biology, disease pathogenesis, and treatment. 雑誌 Clin Microbiol Rev 24:459-68 (2011) DOI:10.1128/CMR.00057-10 |