| H01321 | |
| H番号 | H01321 |
| 名称 | 肺炎球菌感染症 |
| 概要 | Pneumococcal disease (PD) is infectious disease caused by Streptococcus pneumoniae (pneumococcus). PD is particularly common in younger children and in older adults and is roughly divided into invasive and non-invasive disease; the former refers to infections in which the microorganism is isolated from normal sterile body sites, such as the blood or the cerebrospinal fluid. Non-invasive PD can principally be divided into sinusitis, acute otitis media, and community-acquired pneumonia. S. pneumoniae remains the most common bacterial cause of community-acquired pneumonia. The invasive PD burden is mainly determined by pneumococcal meningitis, bacteremic pneumococcal pneumonia, and pneumococcal bacteremia without a primary focus. Incidence and mortality rates of both non-invasive and invasive disease have changed as a result of pneumococcal vaccination in children. However, especially elderly patients with comorbidities remain vulnerable to morbidity and mortality caused by PD. |
| カテゴリ | 細菌感染症 |
| ネットワーク | - |
| 病因遺伝子 | - |
| 病原体 | Streptococcus pneumoniae [GN:spn spd spw spx snd spnn sne spng snp spnm spno] |
| 環境要因 | - |
| 発癌物質 | - |
| 治療薬 | 肺炎球菌ワクチン [DR:D08776] 沈降13価肺炎球菌結合型ワクチン [DR:D10455] 沈降15価肺炎球菌結合型ワクチン [DR:D12205] |
| コメント | - |
| リンク | ICD-11: CA40.07 ICD-10: A40.3 A49.1 MeSH: D011008 |
| 文献 | PMID:24313448 著者 Drijkoningen JJ, Rohde GG タイトル Pneumococcal infection in adults: burden of disease. 雑誌 Clin Microbiol Infect 20 Suppl 5:45-51 (2014) DOI:10.1111/1469-0691.12461 PMID:25343039 著者 Feldman C, Anderson R タイトル Recent advances in our understanding of Streptococcus pneumoniae infection. 雑誌 F1000Prime Rep 6:82 (2014) DOI:10.12703/P6-82 |