H01409 | |
H番号 | H01409 |
名称 | メチシリン感受性黄色ブドウ球菌感染症 |
概要 | Staphylococcus aureus is a Gram-positive human commensal bacterium persistently colonizing the anterior nares of about 30% of the human population. Methicillin-resistant S. aureus (MRSA) is known to have evolved from methicillin-susceptible S. aureus (MSSA) after acquiring the staphylococcal cassette chromosome mec (SCCmec) element which includes the mecA gene coding for resistance to the antibiotic methicillin. A highly cytotoxic and clinically virulent methicillin-sensitive strain, S. aureus strain 6850 is a well-characterized prototype strain isolated from a patient with a skin abscess which had progressed to S. aureus bacteremia, osteomyelitis, septic arthritis, and multiple systemic abscesses. |
カテゴリ | 細菌感染症 疾患パスウェイ hsa05150 黄色ブドウ球菌感染 |
ネットワーク | - |
病因遺伝子 | - |
病原体 | Staphylococcus aureus [GN:sas suc sud saue] |
環境要因 | - |
発癌物質 | - |
治療薬 | - |
コメント | - |
リンク | ICD-10: B95 MeSH: D013203 |
文献 | PMID:24072870 著者 Fraunholz M, Bernhardt J, Schuldes J, Daniel R, Hecker M, Sinha B タイトル Complete Genome Sequence of Staphylococcus aureus 6850, a Highly Cytotoxic and Clinically Virulent Methicillin-Sensitive Strain with Distant Relatedness to Prototype Strains. 雑誌 Genome Announc 1:e00775-13 (2013) DOI:10.1128/genomeA.00775-13 PMID:23183202 著者 Lim KT, Yeo CC, Suhaili Z, Thong KL タイトル Comparison of methicillin-resistant and methicillin-sensitive Staphylococcus aureus strains isolated from a tertiary hospital in Terengganu, Malaysia. 雑誌 Jpn J Infect Dis 65:502-9 (2012) DOI:10.7883/yoken.65.502 |