| H01639 | |
| H番号 | H01639 |
| 名称 | 子宮内膜症 |
| 概要 | Endometriosis is defined as the growth of the endometrial glands and stroma at extra-uterine sites, which are most commonly implanted over and under visceral and peritoneal surfaces within the female pelvis but which can also be found in the connective tissue in the pelvis areas and, more rarely, in any anatomic district. It is a major cause of infertility, dysmenorrhea, dyspareunia, and chronic pelvic pain, mediated by marked pelvic inflammation. While retrograde menstruation is the most widely accepted cause, its pathogenesis and natural course are not fully understood. Endometriosis is known to be an estrogen-dependent disease, manifests during reproductive years. |
| カテゴリ | 生殖器系疾患 |
| ネットワーク | - |
| 病因遺伝子 | - |
| 病原体 | - |
| 環境要因 | - |
| 発癌物質 | - |
| 治療薬 | ジドロゲステロン [DR:D01217] ノルゲストレル・エチニルエストラジオール [DR:D04463] ジエノゲスト [DR:D03799] ダナゾール [DR:D00289] ナファレリン酢酸塩水和物 [DR:D00990] ブセレリン酢酸塩 [DR:D01831] リュープロレリン酢酸塩 [DR:D00989] ゴセレリン酢酸塩 [DR:D00573] レルゴリクス [DR:D10888] 桂枝茯苓丸エキス [DR:D06949] |
| コメント | - |
| リンク | ICD-11: GA10 ICD-10: N80 MeSH: D004715 |
| 文献 | PMID:24927773 著者 Aznaurova YB, Zhumataev MB, Roberts TK, Aliper AM, Zhavoronkov AA タイトル Molecular aspects of development and regulation of endometriosis. 雑誌 Reprod Biol Endocrinol 12:50 (2014) DOI:10.1186/1477-7827-12-50 PMID:24366116 著者 Vercellini P, Vigano P, Somigliana E, Fedele L タイトル Endometriosis: pathogenesis and treatment. 雑誌 Nat Rev Endocrinol 10:261-75 (2014) DOI:10.1038/nrendo.2013.255 PMID:26125255 著者 Soave I, Caserta D, Wenger JM, Dessole S, Perino A, Marci R タイトル Environment and Endometriosis: a toxic relationship. 雑誌 Eur Rev Med Pharmacol Sci 19:1964-72 (2015) |