| H01651 | |
| H番号 | H01651 |
| 名称 | 黄斑浮腫 |
| 概要 | Macular edema is a common feature of many diseases of the retina, such as intraocular inflammation (uveitis), central or branch retinal vein occlusion, diabetic retinopathy and following cataract extraction. It is characterized by a retinal thickening in the macular area due to the breakdown of the blood-retinal barrier. Extracellular fluid accumulates in the intraretinal area or collects in the subretinal space. In more severe cases, it occurs as cystoid edema with the typical petaloid appearance, and is the leading cause of visual loss. New treatments for macular edema have emerged over the past decade, the most recent and efficacious of which have involved blockage of vascular endothelial growth factor (VEGF) by frequent intravitreal injection of pharmacologic agents. |
| カテゴリ | 神経系疾患 |
| ネットワーク | - |
| 病因遺伝子 | - |
| 病原体 | - |
| 環境要因 | - |
| 発癌物質 | - |
| 治療薬 | トリアムシノロンアセトニド [DR:D00983] アフリベルセプト [DR:D09574] ラニビズマブ [DR:D05697] ブロルシズマブ [DR:D11083] ファリシマブ [DR:D11516] |
| コメント | - |
| リンク | ICD-11: 9B75.Y ICD-10: H35.8 MeSH: D008269 OMIM: 153880 |
| 文献 | PMID:19668445 著者 Rotsos TG, Moschos MM タイトル Cystoid macular edema. 雑誌 Clin Ophthalmol 2:919-30 (2008) DOI:10.2147/opth.s4033 PMID:21860693 著者 Romero-Aroca P タイトル Managing diabetic macular edema: The leading cause of diabetes blindness. 雑誌 World J Diabetes 2:98-104 (2011) DOI:10.4239/wjd.v2.i6.98 PMID:27256304 著者 Fardeau C, Champion E, Massamba N, LeHoang P タイトル Uveitic macular edema. 雑誌 Eye (Lond) 30:1277-1292 (2016) DOI:10.1038/eye.2016.115 PMID:27330464 著者 Andreoli MT, Pinnolis M, Kieser T, Sun J, Andreoli CM タイトル Feasibility and efficacy of a mass switch from ranibizumab (Lucentis) to bevacizumab (Avastin) for treatment of neovascular age-related macular degeneration. 雑誌 Digit J Ophthalmol 21:1-17 (2015) DOI:10.5693/djo.01.2015.04.002 |